Blessed Domenico Mazzarella (9 September 1802 – 4 July 1854) was an Italian Roman Catholic priest. He was also a professed member of the Franciscan Friars Minor of the Alcantarines and assumed the name of "Modestino of Jesus and Mary". He devoted his life to service to those who were poor and sick and he himself later succumbed to cholera during an epidemic as he tended to the ill. He was beatified in 1995.