Sclerocactus mesae-verde, Mesa Verde cactus or Mesa Verde fishhook cactus, is a species of cactus in the Sclerocactus genus occurring in habitat at 4000–5000 ft. only in Colorado and New Mexico in the Four Corners region, United States. This species was discovered near Cortez and Mesa Verde by Charles H. Boissevain, and is the only known population group in Colorado. Sclerocactus mesae-verde was formerly classified in the monotypic genus Coloradoa.