Epacadostat
Epacadostat (previously INCB24360) is an investigational drug for cancer. Epacadostat is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1). Epacadostat inhibits IDO1 by competitively blocking it, without interfering with IDO2 or tryptophan 2,3-dioxygenase (TDO). It has antitumor activity in some models, though is most effective when combined with other immunotherapy agents.
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Epacadostat
Epacadostat (previously INCB24360) is an investigational drug for cancer. Epacadostat is an inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1). Epacadostat inhibits IDO1 by competitively blocking it, without interfering with IDO2 or tryptophan 2,3-dioxygenase (TDO). It has antitumor activity in some models, though is most effective when combined with other immunotherapy agents.
has abstract
Epacadostat (previously INCB24 ...... th other immunotherapy agents.
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CAS number
1204669-58-8
DrugBank
FDA UNII code
71596A9R13
KEGG
Wikipage page ID
50,768,116
page length (characters) of wiki page
Wikipage revision ID
984,447,121
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ATC prefix
L01
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ATC suffix
XX58
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CAS number
ChemSpiderID
34,448,418
DrugBank
DB11717
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IUPAC name
N--N′-hydroxy-4-{[2-ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide
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KEGG
D11049
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SMILES
c1ccF
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StdInChIKey
FBKMWOJEPMPVTQ-UHFFFAOYSA-N
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UNII
wikiPageUsesTemplate
comment
Epacadostat (previously INCB24 ...... th other immunotherapy agents.
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label
Epacadostat
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