Addressin
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a protein that in humans is encoded by the MADCAM1 gene. The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.
Cell adhesion moleculeDuodenal-type follicular lymphomaGut-specific homingHigh endothelial venulesIgSF CAMImmunoglobulin I-set domainL-selectinLeukocyte extravasationList of human protein-coding genes 2Lymph node stromal cellLymphocyteLymphocyte homing receptorMADCAM1MADCAM1 (gene)MAdCAM-1MadCAM-1MadCAM1Mucosal vascular addressin cell adhesion molecule 1 (MADCAM1)NatalizumabOutline of immunology
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Addressin
Mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a protein that in humans is encoded by the MADCAM1 gene. The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.
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Mucosal vascular addressin cel ...... similar to ICAM-1 and VCAM-1.
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Mucosal vascular addressin cel ...... similar to ICAM-1 and VCAM-1.
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Addressin
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