Holoaden bradei, or the Itatiaia highland frog, is a species of frog in the family Craugastoridae. It is endemic to the Itatiaia Mountains of southeastern Brazil. It is restricted to an area of 10 km2 at an elevation of 2,400 to 2,600, the type locality being at 22°21′S, 44°44′W at a location known as Alto Itatiaia. H. bradei is found among stones, mulch, and terrestrial bromeliads, in which it breeds through direct development. H. bradei may already be extinct in the wild because it has not been recorded in the wild for several decades.