Pangenesis was Charles Darwin's hypothetical mechanism for heredity, in which he proposed that each part of the body continually emitted its own type of small organic particles called gemmules that aggregated in the gonads, contributing heritable information to the gametes. He presented this 'provisional hypothesis' in his 1868 work The Variation of Animals and Plants Under Domestication, intending it to fill what he perceived as a major gap in evolutionary theory at the time. The etymology of the word comes from the Greek words pan (a prefix meaning "whole", "encompassing") and genesis ("birth") or genos ("origin"). Pangenesis mirrored ideas originally formulated by Hippocrates and other pre-Darwinian scientists, but built off of new concepts such as cell theory, explaining cell developme