Prostaglandin D2
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by mast cells – recruits Th2 cells, eosinophils, and basophils. In mammalian organs, large amounts of PGD2 are found only in the brain and in mast cells. It is critical to development of allergic diseases such as asthma. Research carried out in 1989 found PGD2 is the primary mediator of vasodilation (the "niacin flush") after ingestion of niacin (nicotinic acid).
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate12-Hydroxyheptadecatrienoic acid15-hydroxyprostaglandin-D dehydrogenase (NADP+)5-Hydroxyeicosanoid dehydrogenaseAKR1C3AcipimoxC20H32O5CYP4F8ChemotaxisEicosanoidEicosanoid receptorEosinophilic bronchitisEoxinHydroxycarboxylic acid receptor 2ILC2Innate lymphoid cellLaropiprantLeukotriene B4 receptor 2List of MeSH codes (D10)List of MeSH codes (D23)MaleMast cellN-Acylethanolamine1,2-dimethoxyethaanOsamu HayaishiPGD2Pattern hair lossPerrottetineneProstacyclin receptorProstaglandinProstaglandin-D synthase1,2-dimethoxyethaanProstaglandin D2 receptorProstaglandin D2 synthaseProstaglandin DP1 receptorProstaglandin DP2 receptorProstaglandin EP1 receptorProstaglandin EP2 receptorProstaglandin EP3 receptorProstaglandin EP4 receptor
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Prostaglandin D2
Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by mast cells – recruits Th2 cells, eosinophils, and basophils. In mammalian organs, large amounts of PGD2 are found only in the brain and in mast cells. It is critical to development of allergic diseases such as asthma. Research carried out in 1989 found PGD2 is the primary mediator of vasodilation (the "niacin flush") after ingestion of niacin (nicotinic acid).
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A prostaglandina D2 (PGD2) é u ...... el da microvasculatura renal).
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La prostaglandina D2 (o PGD2) ...... alérgicas tales como el asma.
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La prostaglandine D2 (PGD2) es ...... de l'alopécie androgénétique.
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Prostaglandin D2 (oder kurz: P ...... D2 bei Alopezie entgegenwirkt.
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Prostaglandin D2 (or PGD2) is ...... re already in clinical trials.
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前列腺素D2（PGD2）是前列腺素的一種。 哺乳動物體內，大 ...... 的，因此數種使用PGD2的哮喘藥都開始尋求減少其用量的方法。
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IUPAC name
9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
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999,218,147
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438,483,782
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A prostaglandina D2 (PGD2) é u ...... landina precursora PGH2 pela .
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La prostaglandina D2 (o PGD2) ...... alérgicas tales como el asma.
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La prostaglandine D2 (PGD2) es ...... lergiques telles que l'asthme.
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Prostaglandin D2 (oder kurz: P ...... D2 bei Alopezie entgegenwirkt.
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Prostaglandin D2 (or PGD2) is ...... on of niacin (nicotinic acid).
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前列腺素D2（PGD2）是前列腺素的一種。 哺乳動物體內，大 ...... 的，因此數種使用PGD2的哮喘藥都開始尋求減少其用量的方法。
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Prostaglandin D2
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Prostaglandin D2
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Prostaglandina D2
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Prostaglandina D2
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Prostaglandine D2
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前列腺素D2
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