Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
about
Shepherding AKT and androgen receptor by Ack1 tyrosine kinaseCross talk of tyrosine kinases with the DNA damage signaling pathwaysPI3K and AKT: Unfaithful Partners in CancerThe PI3K/AKT Pathway and Renal Cell CarcinomaPosttranslational regulation of Akt in human cancerProtein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factorDevelopment of novel ACK1/TNK2 inhibitors using a fragment-based approachPI3K-independent AKT activation in cancers: a treasure trove for novel therapeuticsAck1 tyrosine kinase activation correlates with pancreatic cancer progressionAck1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancerACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferationDrosophila activated Cdc42 kinase has an anti-apoptotic functionModulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxiaDevelopment of a human breast-cancer derived cell line stably expressing a bioluminescence resonance energy transfer (BRET)-based phosphatidyl inositol-3 phosphate (PIP3) biosensorSurvey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerH2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genesACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1SP600125 induces Src and type I IGF receptor phosphorylation independent of JNKDeterminants of the tumor suppressor INPP4B protein and lipid phosphatase activitiesMultiple host kinases contribute to Akt activation during Salmonella infection.Regulation of ack-family nonreceptor tyrosine kinases.ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers.Non-canonical Activation of Akt in Serum-Stimulated Fibroblasts, Revealed by Comparative Modeling of Pathway DynamicsImp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic AnalysisGlobal phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma.Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells.Akt-mediated foxo1 inhibition is required for liver regeneration.Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules.Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer.Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity.Src promotes castration-recurrent prostate cancer through androgen receptor-dependent canonical and non-canonical transcriptional signatures.Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis.The non-receptor tyrosine kinase TNK2/ACK1 is a novel therapeutic target in triple negative breast cancer.Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer.Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung.Akt/PKB: one kinase, many modifications.ACK1 promotes gastric cancer epithelial-mesenchymal transition and metastasis through AKT-POU2F1-ECD signalling.
P2860
23e9d52fc74d8ad5cfcda14b45f8d80ed19384bb2a0bd082aac7e199a47aceeb4458144c1e131b357b9b4054eedb4818a036b6de59718fc624fad43a9b920814a94732ff456cf22e941278d8c8b3030fb900c60683ca696bc8ceb7ef3cc7aeca16171e7ecbfa9d8b8f34d3471970ee7794f967af3be379d4d3224b094f4939ffb78619555e79e5975cb6aeacf2d82ec2e7df12e9fa646821574e448f71c81c0c
P248
Q24308859-044D94A9-45C9-4A9F-999F-468E9DF78731Q26778614-15E8E926-B476-4DD1-843A-242191E8A26AQ26781367-2D1DB562-990E-4992-B3AB-5DEB8BEAEA10Q26800216-A92E5013-2249-4A66-BEDC-419ADA707461Q27027815-1D7C87E6-DC33-4ED2-8AEC-4C8D8CBD595DQ28115391-71925C1A-DB6E-4A34-A05E-2DB62C96F931Q28257452-EFFD4927-9615-4A88-A949-5DEA6A11AA54Q28259003-03805650-D812-49D8-A551-574ACE9E3C0FQ28259414-3F303EB6-8E4B-41BD-B0FA-DA6B45098D37Q28266168-49460D87-C1DA-4936-B954-10E804366263Q28289188-55FF7C02-32DF-47BC-9583-87AE32636F4EQ28483782-17434952-760C-47B2-878C-C9946C46C286Q28534963-84BE4FB0-0900-494B-B227-12D5EB70D90DQ28541161-02768AE3-C3EA-4270-B20B-2E1BD18831E6Q30821888-F0F8B220-9AAF-4294-B09D-91B355856AB8Q34268347-3037CFC0-0231-4B97-AFC6-8D822F52BD15Q34293504-B34A4774-6A3A-4FA1-A74E-67B3EA5F317DQ34317299-1B053308-9D4E-4AFC-81A8-6557C05A04CFQ34359030-654AFF73-9903-4DC0-B299-EC1632D00C4CQ34373594-AB0BA9A4-485A-48BC-B844-B120C18A777EQ34976965-D4DFE103-ED39-4D3F-8FED-27A5C14986B9Q35006333-A1DD10CB-A586-40BF-B3CB-14F1F0AF5674Q35542942-B9DD174D-251F-4FDD-8990-807743E16B3FQ35836933-69EE23B4-3FB2-4D29-9B08-199F4D472E34Q36214062-B8C608EB-CCB9-4449-8D1B-D283943558A4Q36437173-1D4EA328-D31D-457A-9D23-B1F1E5BE0142Q36557240-B2D50D08-FDB4-43C0-8D31-D6E986333761Q36562108-02D93C1A-268F-4142-8B0E-DA9F31BE59B5Q37459257-5C9D25D6-ACF8-465B-A85C-8B11E000B93BQ37525730-388B1DB9-B5C7-48F4-BAFE-91804C2A9EEEQ37558689-EE507E58-DB52-4D52-9F61-33BA6F9D2D96Q37596010-95E539F5-91D2-42CD-9203-3ED070C3EE82Q37635634-8BD66E0E-7F0B-4234-8990-64A2210772FBQ37705831-C2A49C39-E86B-4193-A0AA-C8278DBC2A2EQ37708928-41A3034E-B04B-4393-84AD-252390A2E8CCQ37709408-0C6BC462-FCAA-44AA-B74B-087F1E48D886Q38112122-19569D42-8398-4FFD-9966-6B0880DF9BB7Q38390024-FAB64FF5-443D-4424-BB72-62395E14ACDAQ38495836-B16D526A-DDBA-46AC-A030-F295744C48DAQ38910111-D42EC3BA-AA6E-4DA6-8F2B-BDDEC64038B6
P2860
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@ast
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en-gb
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@nl
type
label
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@ast
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en-gb
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@nl
altLabel
Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation
@en
prefLabel
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@ast
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en-gb
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@nl
P2093
P2860
P921
P1433
P1476
Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
@en
P2093
Alexis S Lopez
Charlene Rivera
Domenico Coppola
Ernst Schönbrunn
H Shelton Earp
Jin Q Cheng
John Koomen
Kiran Mahajan
Nupam P Mahajan
P2860
P356
10.1371/JOURNAL.PONE.0009646
P407
P577
2010-01-01T00:00:00Z