Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding
about
Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionTracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4EConservation of the deadenylase activity of proteins of the Caf1 family in humanThe structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complexUNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinantComponents of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domainThe Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferationRNA processing and modification protein, carbon catabolite repression 4 (Ccr4), arrests the cell cycle through p21-dependent and p53-independent pathwayThe Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescenceAn unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodiesHuman Ccr4-Not complexes contain variable deadenylase subunitsTethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayCcr4-Not complex: the control freak of eukaryotic cellsMechanisms of deadenylation-dependent decayNocturnin: at the crossroads of clocks and metabolismHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexCrystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificitySaccharomyces cerevisiae Ngl3p is an active 3'-5' exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases.Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnoverMessenger RNA turnover in eukaryotes: pathways and enzymesDeadenylation is prerequisite for P-body formation and mRNA decay in mammalian cellsThe circadian deadenylase Nocturnin is necessary for stabilization of the iNOS mRNA in miceImmediate early response of the circadian polyA ribonuclease nocturnin to two extracellular stimuli.Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- miceA circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation.Insights into the structure and architecture of the CCR4-NOT complexPosttranscriptional regulation of mammalian circadian clock output.NOC out the fat: a short review of the circadian deadenylase Nocturnin.Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.mRNA decay enzymes: decappers conserved between yeast and mammals.In vitro analysis of RNA degradation catalyzed by deadenylase enzymes.mRNA deadenylation by PARN is essential for embryogenesis in higher plantsImportant miRs of pathways in different tumor types.Skeletal aging and the adipocyte program: New insights from an "old" molecule.A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.PPARγ: a circadian transcription factor in adipogenesis and osteogenesis.Intermolecular interactions within the abundant DEAD-box protein Dhh1 regulate its activity in vivo
P2860
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P2860
Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding
description
2001 nî lūn-bûn
@nan
2001 թուականին հրատարակուած գիտական յօդուած
@hyw
2001 թվականին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@ast
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en-gb
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@nl
type
label
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@ast
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en-gb
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@nl
prefLabel
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@ast
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en-gb
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@nl
P2093
P2860
P356
P1433
P1476
Identification of four familie ...... ential for hCAF1/hPOP2 binding
@en
P2093
P2860
P2888
P356
10.1186/1471-2164-2-9
P407
P577
2001-01-01T00:00:00Z
P5875
P6179
1012144037