Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
about
SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4-mediated signaling through different mechanismsToll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-betaSIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signalingRegulatory Role of IL-1R8 in Immunity and DiseaseBiomarkers of postoperative delirium and cognitive dysfunctionPU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 geneInterleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKsIL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transductionNF-kappaB and the immune responseSignal transduction by the lipopolysaccharide receptor, Toll-like receptor-4Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signalingNegative regulation of toll-like receptor-mediated immune responsesThe largely normal response to Toll-like receptor 7 and 9 stimulation and the enhanced expression of SIGIRR by B cells in systemic lupus erythematosus.Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils.TLR2, TLR4 and the MyD88 signaling are crucial for the in vivo generation and the longevity of long-lived antibody-secreting cells.Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.SIGIRR participates in negative regulation of LPS response and tolerance in human bladder epithelial cells.Innate pathways to B-cell activation and tolerance.Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome.Genetics of the innate immune response in inflammatory bowel disease.Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.The negative regulation of Toll-like receptor and associated pathways.NF-kappaB and the intestine: friend or foe?Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor Superfamily.Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family.Significance of toll-like receptors expression in tumor growth and spreading: a short reviewHuman Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.β-Thalassemia trait association with autoimmune diseases: β-globin locus proximity to the immunity genes or role of hemorphins?Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer.SIGIRR, a negative regulator of colon tumorigenesis.Therapeutic potential of SIGIRR in systemic lupus erythematosus.Allergic airway inflammation: unravelling the relationship between IL-37, IL-18Rα and Tir8/SIGIRR.Preventing Overheating: Tight Control of Gut Innate Immunity in Health and Disease.Cytokine decoy and scavenger receptors as key regulators of immunity and inflammation.Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures.Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.
P2860
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P2860
Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification and characteriz ...... btype of the IL-1R superfamily
@ast
Identification and characteriz ...... btype of the IL-1R superfamily
@en
Identification and characteriz ...... btype of the IL-1R superfamily
@en-gb
Identification and characteriz ...... btype of the IL-1R superfamily
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type
label
Identification and characteriz ...... btype of the IL-1R superfamily
@ast
Identification and characteriz ...... btype of the IL-1R superfamily
@en
Identification and characteriz ...... btype of the IL-1R superfamily
@en-gb
Identification and characteriz ...... btype of the IL-1R superfamily
@nl
prefLabel
Identification and characteriz ...... btype of the IL-1R superfamily
@ast
Identification and characteriz ...... btype of the IL-1R superfamily
@en
Identification and characteriz ...... btype of the IL-1R superfamily
@en-gb
Identification and characteriz ...... btype of the IL-1R superfamily
@nl
P3181
P356
P1433
P1476
Identification and characteriz ...... btype of the IL-1R superfamily
@en
P2093
Renshaw BR
Thomassen E
P304
P3181
P356
10.1006/CYTO.1998.0452
P407
P50
P577
1999-06-01T00:00:00Z