Mitochondrial DNA stress primes the antiviral innate immune response - Wikidata - awgldk - TriplyDB

Mitochondrial DNA stress primes the antiviral innate immune response

Mitochondrial DNA stress primes the antiviral innate immune response

http://www.wikidata.org/entity/Q23030015

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The rise of mitochondria in medicine Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems.Shutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common Themes STING: infection, inflammation and cancer Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer Mitochondrial DNA: A disposable genome?Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer Sending Out an SOS: Mitochondria as a Signaling Hub DNA sensor cGAS-mediated immune recognition Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation Mitochondria in lung disease Nuclear DNA damage signalling to mitochondria in ageing The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases Dengue virus activates cGAS through the release of mitochondrial DNA Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage Mitochondrial Control of Innate Immunity and Inflammation Identification of a small molecule that primes the type I interferon response to cytosolic DNA.Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity.Regulation of the H+-ATP synthase by IF1: a role in mitohormesis.Mitochondrial Transcription Factor A (TFAM) Binds to RNA Containing 4-Way Junctions and Mitochondrial tRNA.Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.UPR(mt)-mediated cytoprotection and organismal aging.The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent.The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects.Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import.Mitochondrial DNA in the regulation of innate immune responses TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice Loss of Adipose Fatty Acid Oxidation Does Not Potentiate Obesity at Thermoneutrality Mitochondrial DNA copy number variation across human cancers Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS The Mitochondrial Basis of Aging.Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.

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Mitochondrial DNA stress primes the antiviral innate immune response

http://www.wikidata.org/entity/Q23030015

description

2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial DNA stress primes the antiviral innate immune response

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Akiko Iwasaki

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Brett A Duguay

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Cristiana M Pineda

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Donna A MacDuff

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Gerald S Shadel

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Matthew Staron

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Megan Bestwick

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Nuno Raimundo

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Robert E Means

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Sabine M Lang

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P2860

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Cytosolic sensing of viruses

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

EXOG, a novel paralog of Endonuclease G in higher eukaryotes

Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

TM4: a free, open-source system for microarray data management and analysis

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

Mitochondria and cancer

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631831

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10.1038/NATURE14156

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A. Phillip West

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2015-04-23T00:00:00Z

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1048355724

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25642965

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mitochondrial DNA

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4409480

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