A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
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HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxisThe essential role of profilin in the assembly of actin for microspike formation.PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaDimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1HsA novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathwayStructure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' proteinStructure of the small G protein Cdc42 bound to the GTPase-binding domain of ACKMSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblastsPSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organizationGene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent streCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationMAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinaseSPECs, small binding proteins for Cdc42The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changesThe kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylationCdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actinAtypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structuresHuman homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase CMST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activationBorg proteins control septin organization and are negatively regulated by Cdc42A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.POSH2 is a RING finger E3 ligase with Rac1 binding activity through a partial CRIB domainStructure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 bindingHuman CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathwaysA direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosisThe Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formationThe Slit/Robo system suppresses hepatocyte growth factor-dependent invasion and morphogenesis.HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathwayActivation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganizationInduction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASPCharacterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by membrane depolarization via calcineurinKank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1Molecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brainActivation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinaseInteraction of Nck-associated protein 1 with activated GTP-binding protein Rac
P2860
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P2860
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@ast
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@en
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@nl
type
label
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@ast
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@en
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@nl
prefLabel
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@ast
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@en
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@nl
P2093
P2860
P3181
P356
P1476
A conserved binding motif defi ...... for both Cdc42 and Rac GTPases
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.270.49.29071
P407
P577
1995-12-08T00:00:00Z