A ubiquitin ligase complex assembles linear polyubiquitin chains
about
Structural analysis of the UBA domain of X-linked inhibitor of apoptosis protein reveals different surfaces for ubiquitin-binding and self-associationA large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathwayLUBAC synthesizes linear ubiquitin chains via a thioester intermediateThe linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisOTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinOTULIN restricts Met1-linked ubiquitination to control innate immune signalingSHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complexSHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosisA20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiencyThe UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic functionA non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complexUbiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysisInvolvement of linear polyubiquitylation of NEMO in NF-kappaB activationUSP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondriaMolecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chainsLUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMODifferential regulation of RNF8-mediated Lys48- and Lys63-based poly-ubiquitylationHOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complexStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionDistinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chainsQuantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradationCharacterization of polyubiquitin chain structure by middle-down mass spectrometryUbc13: the Lys63 ubiquitin chain building machinePost-translational modifications as key regulators of TNF-induced necroptosisThe Ubiquitination of NF-κB Subunits in the Control of TranscriptionPoly-ubiquitination in TNFR1-mediated necroptosisUbiquitin modificationsRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisNF-κB, the first quarter-century: remarkable progress and outstanding questionsInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationWhen ubiquitin meets NF-κB: a trove for anti-cancer drug developmentRBR E3 ubiquitin ligases: new structures, new insights, new questionsThe role of ubiquitylation in immune defence and pathogen evasionUbiquitin-dependent regulation of Foxp3 and Treg functionProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesUbiquitin in the immune systemLinear ubiquitination signals in adaptive immune responsesDifferential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights
P2860
Q21560897-F2062018-0557-4D98-BC95-380137DB2366Q21562478-9BF792C0-71D7-4239-A5D9-7A37249C8FCDQ24293061-1637A7D5-30AE-4368-B4CE-02E1038470B2Q24293633-429AF7AA-91B7-4B38-9154-2614B59964DAQ24294696-6B2F1136-1AEE-49C0-B6AF-7DE8C686B6A2Q24296844-A6E931D6-D14F-460A-A536-48111351B16FQ24298605-0A72CADA-7DD5-4B09-A7AF-01DD5EE8EED0Q24298626-BC4BC7E0-5481-456D-A788-86195353F00DQ24300148-BB6DE447-2252-4C96-857E-1DD43DB8BFFDQ24301912-9BDE508F-34A8-4413-BC4C-7EBDD66BA621Q24305086-A11EDE0A-7502-46B9-B1C0-9C3C3F57CCF2Q24307922-D534D33D-5B3E-431A-9DBC-378C294489E6Q24310659-6C064E1D-0D05-47A0-B808-93C85557334EQ24315943-A9BECE2B-90C4-4DE8-8C79-34BDE028F4DCQ24316174-00AD14C3-866A-4654-9B12-BF6D2739FD1DQ24316967-359A91E1-AA87-4C6C-AA28-FC21A06C10B3Q24318791-B3ADE8AF-BA55-4AD5-BFFF-A5F07D53ABA7Q24337753-FA44F170-B579-43E2-9809-3C2103A4259CQ24338233-FB1D4522-404E-4830-9A60-8044B5BF67B0Q24339442-1D0F102B-16A3-402F-986F-9C64735C80B3Q24621713-41676208-0AA7-4260-A7AF-61544549FDF7Q24643067-B3BBF819-58DE-4876-8FF0-F9D8673C9A6DQ24649876-94679C57-83F1-431D-9404-C407A6B64087Q26739716-71D20F35-E427-459A-925E-399FA41E07BEQ26744244-180A6F00-F66E-4A80-A3B8-F5C4FB47DBA8Q26748938-A68A5B17-5428-4660-9C27-AA10FD517DA4Q26749315-12C651B6-1097-4014-BB1C-AD11F781ED7AQ26751380-201EDC19-7401-4E93-8EDC-9BB23E0ADAA4Q26778774-617C319C-0E58-43CE-A23B-A9149CFB3099Q26782575-32999FEF-7AD9-4BA2-9118-36938198BCD2Q26822516-B6000C0D-4638-40DF-8C1B-CCD6E94EADDFQ26824586-6DB1BC59-12C6-415E-B8E9-B9846E042C41Q26827754-41AD7832-69B2-466F-A212-D3CC43A6EBB7Q26828565-043967F8-9A94-4115-8613-F1804170F199Q26860775-2639B41D-6CBA-4B1C-93B0-87BB56BD2261Q26863525-F51F414E-5A30-43D0-A764-3BBE117FE7E7Q26865081-A458CAAE-A0F3-4877-9EC5-20F083DE6EA1Q26998711-D6948893-B690-47FA-82EE-DE856F759E98Q27027872-59AC3275-C639-456F-99AF-31401205C817Q27651014-BEC37A3C-6414-475E-B9C6-6D08366A8A9B
P2860
A ubiquitin ligase complex assembles linear polyubiquitin chains
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A ubiquitin ligase complex assembles linear polyubiquitin chains
@ast
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en-gb
A ubiquitin ligase complex assembles linear polyubiquitin chains
@nl
type
label
A ubiquitin ligase complex assembles linear polyubiquitin chains
@ast
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en-gb
A ubiquitin ligase complex assembles linear polyubiquitin chains
@nl
prefLabel
A ubiquitin ligase complex assembles linear polyubiquitin chains
@ast
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en-gb
A ubiquitin ligase complex assembles linear polyubiquitin chains
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
A ubiquitin ligase complex assembles linear polyubiquitin chains
@en
P2093
Fuminori Tokunaga
Hiromi Fukumoto
Kazuhiro Iwai
Keiji Tanaka
Kiyoko Kamei
Masato Kanie
Michiko Kato
Soichi Sano
Takayoshi Kirisako
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601360
P407
P577
2006-10-18T00:00:00Z