A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response
about
Insulin receptor signaling in normal and insulin-resistant statesInvolvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseasesInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesConstitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic programTat-haFGF14-154 Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1α/XBP1 Pathway.BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3KRegulation of basal cellular physiology by the homeostatic unfolded protein responseCrohn's disease: NOD2, autophagy and ER stress converge.The PI3K regulatory subunits p55α and p50α regulate cell death in vivo.FoxO1 links hepatic insulin action to endoplasmic reticulum stress.Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance.The critical role of GRP78 in physiologic and pathologic stress.NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancerHepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liverEndoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevityDefective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolismA p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.Endoplasmic reticulum stress and insulin resistance post-trauma: similarities to type 2 diabetes.Arabidopsis AtPLC2 Is a Primary Phosphoinositide-Specific Phospholipase C in Phosphoinositide Metabolism and the Endoplasmic Reticulum Stress Response.Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells.Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cellsPERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiationEndoplasmic reticulum stress in liver disease.ENDOPLASMIC RETICULUM STRESS IN SEPSIS.Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis.Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein ExpressionSilencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.Urinary neutrophil gelatinase-associated lipocalin is associated with heavy metal exposure in welding workers.Hepatic Xbp1 Gene Deletion Promotes Endoplasmic Reticulum Stress-induced Liver Injury and ApoptosisPhosphoinositide 3-kinase-δ regulates fungus-induced allergic lung inflammation through endoplasmic reticulum stressThe Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism.Vascular complications of diabetes: mechanisms of injury and protective factorsSHORT syndrome with partial lipodystrophy due to impaired phosphatidylinositol 3 kinase signaling.Epigenetic differences in monozygotic twins discordant for major depressive disorderIRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation.Adipose tissue insulin sensitivity and macrophage recruitment: Does PI3K pick the pathway?
P2860
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P2860
A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A regulatory subunit of phosph ...... the unfolded protein response
@ast
A regulatory subunit of phosph ...... the unfolded protein response
@en
A regulatory subunit of phosph ...... the unfolded protein response
@en-gb
A regulatory subunit of phosph ...... the unfolded protein response
@nl
type
label
A regulatory subunit of phosph ...... the unfolded protein response
@ast
A regulatory subunit of phosph ...... the unfolded protein response
@en
A regulatory subunit of phosph ...... the unfolded protein response
@en-gb
A regulatory subunit of phosph ...... the unfolded protein response
@nl
prefLabel
A regulatory subunit of phosph ...... the unfolded protein response
@ast
A regulatory subunit of phosph ...... the unfolded protein response
@en
A regulatory subunit of phosph ...... the unfolded protein response
@en-gb
A regulatory subunit of phosph ...... the unfolded protein response
@nl
P2093
P2860
P3181
P356
P1433
P1476
A regulatory subunit of phosph ...... the unfolded protein response
@en
P2093
Jeremie Boucher
Jonathon N Winnay
Marcelo A Mori
P2860
P2888
P304
P3181
P356
10.1038/NM.2121
P407
P577
2010-04-01T00:00:00Z
P5875
P6179
1016917189