Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation
about
The role of titin and extracellular matrix remodelling in heart failure with preserved ejection fractionTitin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle RemodelingOngoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray?Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapiesMechanisms of altered Ca²⁺ handling in heart failureHeart failure with preserved ejection fractionWhat global diastolic function is, what it is not, and how to measure itS-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.Heart failure with preserved ejection fraction: molecular pathways of the aging myocardiumDifferences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum.Probing muscle ankyrin-repeat protein (MARP) structure and functionCardioprotection and lifespan extension by the natural polyamine spermidine.Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffnessNovel aspects of excitation-contraction coupling in heart failure.Cardiac titin and heart disease.Protein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertensionEmerging importance of oxidative stress in regulating striated muscle elasticity.Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titinPhosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle ForceAtrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signalBest Practice BioBanking of Human Heart TissueTitin stiffness modifies the force-generating region of muscle sarcomeres.The NO/ONOO-cycle as the central cause of heart failure.Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins.The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias.Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.New insights in (inter)cellular mechanisms by heart failure with preserved ejection fraction.Titin mutations: the fall of Goliath.Myocardial reverse remodeling: how far can we rewind?Heart failure with preserved ejection fraction and skeletal muscle physiology.Cardiovascular consequences of metabolic syndrome.Myofilaments: Movers and Rulers of the Sarcomere.Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes.A change of heart: oxidative stress in governing muscle function?Loss of myocardial retinoic acid receptor α induces diastolic dysfunction by promoting intracellular oxidative stress and calcium mishandling in adult mice.CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.Molecular and structural transition mechanisms in long-term volume overload.The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease.Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function.Two Kinases to Soften the Heart.
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Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation
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2013 nî lūn-bûn
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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2013 թվականի փետրվարին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@ast
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en-gb
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
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type
label
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@ast
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en-gb
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@nl
prefLabel
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@ast
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en-gb
Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@nl
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Crucial role for Ca2(+)/calmod ...... arts via titin phosphorylation
@en
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Cristobal G Dos Remedios
Johannes Backs
Judith Krysiak
Lars S Maier
Markus Krüger
Michael M Kreusser
Nazha Hamdani
Stefan Neef
Wolfgang A Linke
P304
P3181
P356
10.1161/CIRCRESAHA.111.300105
P407
P577
2013-02-15T00:00:00Z