The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor
about
MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblastsA mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainNegative regulation of Rho family GTPases Cdc42 and Rac2 by homodimer formationAsef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation elementCDC42 and FGD1 cause distinct signaling and transforming activities.Oligomerization of DH domain is essential for Dbl-induced transformationFGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane rufflesCortactin branches out: roles in regulating protrusive actin dynamicsPeripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4MicroRNA expression characterizes oligometastasis(es)Structure and mutagenesis of the Dbl homology domainCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.A mutation in the pleckstrin homology (PH) domain of the FGD1 gene in an Italian family with faciogenital dysplasia (Aarskog-Scott syndrome)Tyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoATrp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factorsPhenotypic and molecular characterisation of the Aarskog-Scott syndrome: a survey of the clinical variability in light of FGD1 mutation analysis in 46 patientsDystrophin-glycoprotein complex and Ras and Rho GTPase signaling are altered in muscle atrophyCdc42 in oncogenic transformation, invasion, and tumorigenesisCharacterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors. Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domainsActivation of G1 progression, JNK mitogen-activated protein kinase, and actin filament assembly by the exchange factor FGD1Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinaseCcpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor DbsNexilin: a novel actin filament-binding protein localized at cell-matrix adherens junctionVav2 is an activator of Cdc42, Rac1, and RhoAThe Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor β-stimulated aortic endothelial cells.Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish.Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells.The genetic basis of non-syndromic intellectual disability: a reviewRhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.Signal transduction: stuck with FYVE domains.Guanine nucleotide exchange factors regulate specificity of downstream signaling from Rac and Cdc42.A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast.The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes.The Cdc42 guanine nucleotide exchange factor FGD1 regulates osteogenesis in human mesenchymal stem cellsMLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in miceFrabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membraneThe Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.Podosomal proteins as causes of human syndromes: a role in craniofacial development?
P2860
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P2860
The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@ast
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en-gb
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@nl
type
label
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@ast
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en-gb
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@nl
prefLabel
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@ast
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en-gb
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@nl
P2093
P356
P1476
The faciogenital dysplasia gen ...... ine-nucleotide exchange factor
@en
P2093
D J Fischer
J L Gorski
M F Santos
N G Pasteris
P304
P356
10.1074/JBC.271.52.33169
P407
P577
1996-12-27T00:00:00Z