Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
about
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcriptionValosin-containing protein (VCP/p97) is an activator of wild-type ataxin-3Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.The business of deubiquitination - location, location, locationCell biology of spinocerebellar ataxiaAberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtinProteotoxic stress increases nuclear localization of ataxin-3Nucleocytoplasmic shuttling activity of ataxin-3.Polyglutamine pathogenesis.Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.Interaction of expanded polyglutamine stretches with nuclear transcription factors leads to aberrant transcriptional regulation in polyglutamine diseases.The selective vulnerability of nerve cells in Huntington's disease.Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor.Neuronal intranuclear hyaline inclusion disease.Toward understanding Machado-Joseph diseaseRecruitment and the role of nuclear localization in polyglutamine-mediated aggregation.Machado-Joseph disease/spinocerebellar ataxia type 3.Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.Expansion of the polyQ repeats in THAP11 forms intranuclear aggregation and causes cell G0/G1 arrest.Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?Casein kinase 2 interacts with and phosphorylates ataxin-3.Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease.Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease.Divalproex sodium modulates nuclear localization of ataxin-3 and prevents cellular toxicity caused by expanded ataxin-3.Absence of spinocerebellar ataxia type 3/Machado-Joseph disease within ataxic patients in the Czech population.Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways
P2860
Q21144909-67F0F90F-8D8C-496A-A64E-F6C8874665A6Q24290194-9811FF1F-12D2-446F-89C3-93C0D8DBD2EDQ24298529-1D57563A-7CCC-434D-AA94-BD69229D5A3FQ24534867-4EB6E478-193D-4D6E-AD34-6EAC19493449Q26766125-69574680-70F6-4996-9D88-D1DC90BB4E18Q26829511-AFB62216-2F61-4A78-A82D-CD968E9D5CAFQ28141695-C8F8004C-ABC4-4755-B2EC-4065CE391519Q28506165-5A59B6EE-A42B-4078-B469-8E03688D7395Q33463406-D6594901-28B9-4073-992D-B57464104F95Q33703910-1C3B1A98-EC0E-41FA-B4CC-2A5B30C1209FQ33703919-5DD4985C-CE82-4787-9D67-8B9149AAD2F1Q34158010-0E754846-8FDE-43E4-8318-077000186315Q34216757-9CD8C92A-4C6D-427B-BBE8-84C6601A49C9Q34973238-29225960-E984-4C1D-88BC-35B562F43A73Q35627286-3B8C3D18-58A2-448D-9177-0BFA2A4B883AQ35837355-4073B29A-F05E-4A8A-972E-79D15A2794E7Q36255989-30E41F42-58D6-47D0-812B-4F967B5F93ACQ36599588-DDF2EB64-13A5-4356-901B-F849199E6F2AQ38167681-36C95591-8AEC-4996-947A-0CA64E499DFEQ39010713-3D430478-0CB9-4ABD-BE81-28A3828A6605Q39724719-09255B4E-258C-49D7-8CF2-B9C683E8B6BEQ39931946-0BC195CF-F5A4-4009-A185-3550D6EFBCE6Q39995612-D35EF40E-CDB2-4EE2-92D5-1B339EB8DB7CQ40968069-A168D78C-D27F-42DE-8320-DC8148AACB7AQ43577436-FB3D74EE-19EB-43E7-BFC8-7B9E7649525DQ47214748-7D50FE14-08B1-4010-803C-F6FD8A941579Q48721172-47AD2689-1F5A-4B79-9688-5D4192463412Q58720443-D0E4C05D-C709-4614-9080-D486726A73F0
P2860
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@ast
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en-gb
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@nl
type
label
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@ast
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en-gb
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@nl
prefLabel
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@ast
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en-gb
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@nl
P2093
P356
P1476
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
@en
P2093
A Ognibene
E E Wanker
E Scherzinger
N M Maraldi
P356
10.1093/HMG/7.6.991
P407
P577
1998-06-01T00:00:00Z