Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain - Wikidata - awgldk - TriplyDB

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

http://www.wikidata.org/entity/Q24321955

about

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils Highly efficient purification of protein complexes from mammalian cells using a novel streptavidin-binding peptide and hexahistidine tandem tag system: application to Bruton's tyrosine kinase Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Regulation of protein kinases by lipids B cell receptor pathway in chronic lymphocytic leukemia: specific role of CC-292 Small molecules in the treatment of systemic lupus erythematosus The tyrosine kinase Btk regulates the macrophage response to Listeria monocytogenes infection ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).Characterization of all possible single-nucleotide change caused amino acid substitutions in the kinase domain of Bruton tyrosine kinase.Switching immune signals on and off.Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.Bruton's tyrosine kinase regulates Shigella flexneri dissemination in HT-29 intestinal cells Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells Augmented B lymphocyte response to antigen in the absence of antigen-induced B lymphocyte signaling in an IgG-transgenic mouse line Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond.A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-κB pathway.Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats Future therapeutic targets in rheumatoid arthritis?T-cell signaling regulated by the Tec family kinase, Itk.Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model Critical roles of the WASP N-terminal domain and Btk in LPS-induced inflammatory response in macrophages.Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury.Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells.The role of tyrosine kinases in systemic lupus erythematosus and their potential as therapeutic targets.P.Arg82Leu von Hippel-Lindau (VHL) gene mutation among three members of a family with familial bilateral pheochromocytoma in India: molecular analysis and in silico characterization.A novel Bruton's tyrosine kinase gene (BTK) missense mutation in a Chinese family with X-linked agammaglobulinemia.Splice-correction strategies for treatment of X-linked agammaglobulinemia.Clinical and technical phosphoproteomic research.Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.Bruton's TK inhibitors: structural insights and evolution of clinical candidates.Btk29A-mediated tyrosine phosphorylation of armadillo/β-catenin promotes ring canal growth in Drosophila oogenesis.Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells A critical appraisal of ibrutinib in the treatment of mantle cell lymphoma and chronic lymphocytic leukemia Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia.Tyrosine kinase Btk is required for NK cell activation

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Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

http://www.wikidata.org/entity/Q24321955

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մարտին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@ast

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en-gb

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@nl

type

label

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@ast

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en-gb

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@nl

prefLabel

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@ast

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en-gb

Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@nl

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J.1600-065X.2008.00741.X

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Immunological Reviews

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Bruton's tyrosine kinase (Btk) ...... cial emphasis on the PH domain

@en

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Abdalla J Mohamed

http://www.w3.org/2001/XMLSchema#string

Alar Aints

http://www.w3.org/2001/XMLSchema#string

Anna Berglöf

http://www.w3.org/2001/XMLSchema#string

Birger Christensson

http://www.w3.org/2001/XMLSchema#string

Carl-Magnus Bäckesjö

http://www.w3.org/2001/XMLSchema#string

Leonardo Vargas

http://www.w3.org/2001/XMLSchema#string

Liang Yu

http://www.w3.org/2001/XMLSchema#string

Rani Faryal

http://www.w3.org/2001/XMLSchema#string

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Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase

The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.

Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis.

Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production.

A novel role for caveolin-1 in B lymphocyte function and the development of thymus-independent immune responses.

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58-73

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scholarly article

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4783724

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10.1111/J.1600-065X.2008.00741.X

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P433

1

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P478

228

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C. I. Edvard Smith

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2009-03-01T00:00:00Z

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19290921

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P921

positive regulation of NF-kappaB transcription factor activity

Bruton tyrosine kinase