C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
about
Activation of Rac1 by a Crk SH3-binding protein, DOCK180CrkII participation in the cellular effects of growth hormone and insulin-like growth factor-1. Phosphatidylinositol-3 kinase dependent and independent effectsInteraction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)PH domain of ELMO functions in trans to regulate Rac activation via Dock180An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingMembrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processesELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.GEF what? Dock180 and related proteins help Rac to polarize cells in new waysuPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transportThe CDM superfamily protein MBC directs myoblast fusion through a mechanism that requires phosphatidylinositol 3,4,5-triphosphate binding but is independent of direct interaction with DCrkDisruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotypeListeria monocytogenes exploits normal host cell processes to spread from cell to cellDOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxisTip cells: master regulators of tubulogenesis?Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegansClathrin and AP2 are required for phagocytic receptor-mediated apoptotic cell clearance in Caenorhabditis elegansPhagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cellsCaenorhabditis elegans myotubularin MTM-1 negatively regulates the engulfment of apoptotic cellsThe DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS developmentStructural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IVSignaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKLDock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migrationHaematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migrationThe Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearanceRegulation of focal adhesion and cell migration by ANKRD28-DOCK180 interactionThe adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration.The functional role of CrkII in actin cytoskeleton organization and mitogenesis.Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex.Apoptotic cell recognition receptors and scavenger receptors.Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestionThe lysosomal cathepsin protease CPL-1 plays a leading role in phagosomal degradation of apoptotic cells in Caenorhabditis elegans.Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegansSRGP-1 regulation, targets, and contribution to cell killing in C. elegansFind-me and eat-me signals in apoptotic cell clearance: progress and conundrums.Rac1 is essential for basement membrane-dependent epiblast survivalThe novel Cdc42 guanine nucleotide exchange factor, zizimin1, dimerizes via the Cdc42-binding CZH2 domain.
P2860
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P2860
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@ast
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en-gb
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@nl
type
label
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@ast
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en-gb
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@nl
prefLabel
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@ast
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en-gb
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@nl
P2860
P921
P3181
P356
P1433
P1476
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
@en
P2093
P2860
P2888
P3181
P356
10.1038/33163
P407
P577
1998-04-02T00:00:00Z
P5875
P6179
1011167543