Identification of a new membrane-bound heparan sulphate proteoglycan
about
Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndromeMammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brainProcessing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growthGlypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycansExpression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma.Glypicans: proteoglycans with a surprise.Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signalingImmunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis.OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner.Glypican and biglycan in the nuclei of neurons and glioma cells: presence of functional nuclear localization signals and dynamic changes in glypican during the cell cycleSyndecan-1 is up-regulated in ras-transformed intestinal epithelial cells.Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathwayCritical analysis of the potential of targeting GPC3 in hepatocellular carcinoma.Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican‑3‑derived peptideGPC-HCC model: a combination of glybican-3 with other routine parameters improves the diagnostic efficacy in hepatocellular carcinoma.Glypican-3 reexpression regulates apoptosis in murine adenocarcinoma mammary cells modulating PI3K/Akt and p38MAPK signaling pathways.Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation.OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2.Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor.Suppression of glypican 3 inhibits growth of hepatocellular carcinoma cells through up-regulation of TGF-β2.Golgi protein 73, not Glypican-3, may be a tumor marker complementary to α-Fetoprotein for hepatocellular carcinoma diagnosis.Regulation of urokinase/urokinase receptor interaction by heparin-like glycosaminoglycans.Inhibition of invasion and metastasis by glypican-3 in a syngeneic breast cancer model.Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent.Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomas.Combining expression of GPC3 in tumors and CD16 on NK cells from peripheral blood to identify patients responding to codrituzumab.Glypican-3 is overexpressed in human hepatocellular carcinoma.Glypicans: a growing trend
P2860
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P2860
Identification of a new membrane-bound heparan sulphate proteoglycan
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Identification of a new membrane-bound heparan sulphate proteoglycan
@ast
Identification of a new membrane-bound heparan sulphate proteoglycan
@en
Identification of a new membrane-bound heparan sulphate proteoglycan
@en-gb
Identification of a new membrane-bound heparan sulphate proteoglycan
@nl
type
label
Identification of a new membrane-bound heparan sulphate proteoglycan
@ast
Identification of a new membrane-bound heparan sulphate proteoglycan
@en
Identification of a new membrane-bound heparan sulphate proteoglycan
@en-gb
Identification of a new membrane-bound heparan sulphate proteoglycan
@nl
prefLabel
Identification of a new membrane-bound heparan sulphate proteoglycan
@ast
Identification of a new membrane-bound heparan sulphate proteoglycan
@en
Identification of a new membrane-bound heparan sulphate proteoglycan
@en-gb
Identification of a new membrane-bound heparan sulphate proteoglycan
@nl
P2093
P2860
P356
P1433
P1476
Identification of a new membrane-bound heparan sulphate proteoglycan
@en
P2093
P2860
P356
10.1042/BJ3110561
P407
P478
311 ( Pt 2)
P577
1995-10-15T00:00:00Z