Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica
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Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretionType III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactionsYersinia virulence factors - a sophisticated arsenal for combating host defencesV-antigen homologs in pathogenic gram-negative bacteriaBacterial type III secretion systems: specialized nanomachines for protein delivery into target cellsStructure of theYersinia pestistip protein LcrV refined to 1.65 Å resolutionThe Structure and Function of Type III Secretion SystemsModified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosaProtein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion systemProtein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria.Multi-Functional Characteristics of the Pseudomonas aeruginosa Type III Needle-Tip Protein, PcrV; Comparison to Orthologs in other Gram-negative BacteriaLcrG secretion is not required for blocking of Yops secretion in Yersinia pestis.Control of type III secretion activity and substrate specificity by the cytoplasmic regulator PcrG.Amino acid and structural variability of Yersinia pestis LcrV protein.Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapyVp1659 is a Vibrio parahaemolyticus type III secretion system 1 protein that contributes to translocation of effector proteins needed to induce cytolysis, autophagy, and disruption of actin structure in HeLa cells.A program of Yersinia enterocolitica type III secretion reactions is activated by specific signalsThe type III secretion system tip complex and translocon.Rejection of impassable substrates by Yersinia type III secretion machinesIdentification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells.MxiE regulates intracellular expression of factors secreted by the Shigella flexneri 2a type III secretion systemYersinia enterocolitica type III secretion: yscM1 and yscM2 regulate yop gene expression by a posttranscriptional mechanism that targets the 5' untranslated region of yop mRNA.YscP and YscU regulate substrate specificity of the Yersinia type III secretion systemThe ttsA gene is required for low-calcium-induced type III secretion of Yop proteins and virulence of Yersinia enterocolitica W22703Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV.Measurement of effector protein injection by type III and type IV secretion systems by using a 13-residue phosphorylatable glycogen synthase kinase tagCombinational deletion of three membrane protein-encoding genes highly attenuates yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague.Polymorphisms in the lcrV gene of Yersinia enterocolitica and their effect on plague protective immunity.Diminished LcrV secretion attenuates Yersinia pseudotuberculosis virulence.YscU cleavage and the assembly of Yersinia type III secretion machine complexes.Prevention of pneumonic plague in mice, rats, guinea pigs and non-human primates with clinical grade rV10, rV10-2 or F1-V vaccines.LcrV mutants that abolish Yersinia type III injectisome function.Yersinia pestis caf1 variants and the limits of plague vaccine protection.Timing is everything: the regulation of type III secretion.Regulation of the Yersinia type III secretion system: traffic control.Assembly of the bacterial type III secretion machinery.Altered Ca(2+) regulation of Yop secretion in Yersinia enterocolitica after DNA adenine methyltransferase overproduction is mediated by Clp-dependent degradation of LcrG.Regulated secretion of YopN by the type III machinery of Yersinia enterocolitica.Characterization of the type III secretion associated low calcium response genes of Vibrio parahaemolyticus RIMD2210633.Mutations in the Yersinia pseudotuberculosis type III secretion system needle protein, YscF, that specifically abrogate effector translocation into host cells.
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Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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Roles of LcrG and LcrV during ...... ops by Yersinia enterocolitica
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K L DeBord
O Schneewind
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10.1128/JB.183.15.4588-4598.2001
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2001-08-01T00:00:00Z