Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine
about
Functional analysis of missense variants in the TRESK (KCNK18) K channelATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of DiseaseThe Revolution in Migraine Genetics: From Aching Channels Disorders to a Next-Generation MedicineMigraine in the era of precision medicineRoles of renal proximal tubule transport in acid/base balance and blood pressure regulationMolecular mechanisms and regulation of urinary acidificationNBCe1A dimer assemble visualized by bimolecular fluorescence complementationThe divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersNa-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function.Systematic re-evaluation of genes from candidate gene association studies in migraine using a large genome-wide association data set.Calcium channels and synaptic transmission in familial hemiplegic migraine type 1 animal models.NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease.New directions in migraineRole of an extracellular loop in determining the stoichiometry of Na+-HCO₃⁻ cotransporters.The SLC4 family of bicarbonate (HCO₃⁻) transporters.Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography.Rescue of the temperature-sensitive, autosomal-recessive mutation R298S in the sodium-bicarbonate cotransporter NBCe1-A characterized by a weakened dimer and abnormal aggregation.IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues.The role of aspartic acid residues 405 and 416 of the kidney isotype of sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane.NBCe1 expression is required for normal renal ammonia metabolism.Effect of simultaneously replacing putative TM6 and TM12 of human NBCe1-A with those from NBCn1 on surface abundance in Xenopus oocytespH-sensitive self-associations of the N-terminal domain of NBCe1-A suggest a compact conformation under acidic intracellular conditions.Structure and Function of SLC4 Family [Formula: see text] Transporters.Cation-coupled bicarbonate transportersScreening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis.Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.Identification of molecular genetic factors that influence migraine.Functional Roles of Electrogenic Sodium Bicarbonate Cotransporter NBCe1 in Ocular Tissues.Pearls and pitfalls in genetic studies of migraine.Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis.Migraine genetics: Part II.Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO3 (-) cotransporter NBCe1Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties.The role of glia in stress: polyamines and brain disordersClinical and laboratory approaches in the diagnosis of renal tubular acidosis.Pediatric migraine and episodic syndromes that may be associated with migraine.Emerging roles of Na⁺/H⁺ exchangers in epilepsy and developmental brain disorders.Migraine genetics: current findings and future lines of research.Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders.
P2860
Q24602232-282F1595-927E-4076-A64C-25D3E2DD78EEQ26738318-D97FA2FD-B4A9-4273-B69D-E973EDDC321EQ26744657-1C098F3E-FD49-4824-B1D7-1D7A41D380BBQ26748947-14C07293-712B-4821-9DF3-C288E62BA634Q26821934-542A8A63-F2F1-4422-BF5E-CCF3837057FAQ26823086-813C85E6-71A9-44AC-B944-80A439E4B629Q30358469-F81F0D1F-FE42-4E84-A897-00300CFEA18CQ30440948-BB5AD571-0301-47B6-8A2B-80C9E3D61F83Q30471906-99C283C1-E365-4E87-8094-55064E8D5B9BQ30886614-B47D282C-3E2C-461E-B967-190AEF51777DQ33680269-4E848F4B-66A2-484F-B561-46F16EF82D0FQ33894132-C55F63EB-A30A-4624-AB20-FC026427FE26Q34057763-D88DBFAC-2A73-47DF-A6BB-E930EA1074ADQ34158447-D916A599-E42F-45B5-B3EC-768593DFB17DQ34333694-BDE18023-5228-46D4-8838-FC445C56EB6EQ35126595-0444D510-1BA8-479D-8544-3185C1B023A5Q35583441-E210706A-EDA8-4982-9C2F-510FB065BA7CQ35824341-52BBF398-30C0-4E0A-A562-6EAE13D469EEQ36041905-395ACCCF-EC49-4CF6-B2D1-32FE428A3DDDQ36122791-E360E0EF-8131-48DC-BC3F-E751B3491198Q36257173-197EA497-3D37-4F9F-BBC9-820991647F54Q36328803-413D4B0A-2D90-4BAE-A49F-FC93E6DDF8F9Q36333222-BD323EA6-A87C-4E2C-A988-D95DD228B54CQ36623416-9C955C91-1EAD-4273-979C-C31EB945DE40Q37398107-1D7C77BC-D703-41ED-B486-A73D99507940Q37476434-76A5DECF-E955-469C-861B-2A5B73220683Q37679770-372BA051-0DA4-41B9-895A-B167D6203419Q37868982-33E02931-8AFF-4C85-99ED-755A9B8602C7Q38026560-77A8FC85-B1E6-43B1-9272-284747CF255AQ38106687-7BBEAE04-C45C-40FA-87B6-CDF8B5D19990Q38126740-FE57FAA4-CBA8-4FF5-B238-36B01078185EQ38126970-D4CD4FF8-C914-48BC-9A9E-5371BF2B115BQ38150331-A71E418A-8793-41DF-8BAA-83ABB40E9E78Q38175973-2287CBA4-C0CD-42CE-821A-F49F6221D9F9Q38278661-2939E04A-2D23-44D2-A63D-0B80E535D0B5Q38396328-9243C3EB-C864-4926-ABE4-A6ADBAB9BDFCQ38451365-3A393DFF-8F48-45F2-92E0-3CA097903B73Q38769191-5CD7A662-EC58-4FFF-A20C-1ED750855DCAQ39077188-52811286-357B-4A8D-852E-7F098E1D3B9CQ39167599-22C5DD51-0245-4A89-AB56-46DC4BA13CBD
P2860
Defective membrane expression of the Na(+)-HCO(3)(-) cotransporter NBCe1 is associated with familial migraine
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Defective membrane expression ...... ociated with familial migraine
@ast
Defective membrane expression ...... ociated with familial migraine
@en
Defective membrane expression ...... ociated with familial migraine
@nl
type
label
Defective membrane expression ...... ociated with familial migraine
@ast
Defective membrane expression ...... ociated with familial migraine
@en
Defective membrane expression ...... ociated with familial migraine
@nl
prefLabel
Defective membrane expression ...... ociated with familial migraine
@ast
Defective membrane expression ...... ociated with familial migraine
@en
Defective membrane expression ...... ociated with familial migraine
@nl
P2093
P2860
P50
P3181
P356
P1476
Defective membrane expression ...... ociated with familial migraine
@en
P2093
Bruno A Bergmans
Eric Legius
Florence Riant
George Seki
Hideomi Yamada
Ichiro Fujimoto
Ingeborg Stalmans
Masaaki Shiohara
Masashi Suzuki
Mitsunobu Shimadzu
P2860
P304
P3181
P356
10.1073/PNAS.1008705107
P407
P577
2010-09-07T00:00:00Z