Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse
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Tissue-Specific GHR Knockout Mice: Metabolic PhenotypesGrowth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in miceGenome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtiiHypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neuronsThe Role of the Growth Hormone/Insulin-Like Growth Factor System in Visceral Adiposity.A dwarf mouse model with decreased GH/IGF-1 activity that does not experience life-span extension: potential impact of increased adiposity, leptin, and insulin with advancing age.The GH/IGF-1 axis in ageing and longevityInsulin-like growth factor 1 physiology: lessons from mouse models.The impact of growth hormone on proteomic profiles: a review of mouse and adult human studies.Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on hormones of energy balance in a TCDD-sensitive and a TCDD-resistant rat strain.hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signalingAging and dry eye diseaseDisruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH.DLK1/PREF1 regulates nutrient metabolism and protects from steatosis.Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependentGene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.Metabolic outcome of female mice exposed to a mixture of low-dose pollutants in a diet-induced obesity model.Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.Ablation of the transcriptional regulator Id1 enhances energy expenditure, increases insulin sensitivity, and protects against age and diet induced insulin resistance, and hepatosteatosis.Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice.Syntaxin 4 Overexpression Ameliorates Effects of Aging and High-Fat Diet on Glucose Control and Extends LifespanAge- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice.Generation of a miniature pig disease model for human Laron syndromeGonadotropin-releasing hormone receptor (Gnrhr) gene knock out: Normal growth and development of sensory, motor and spatial orientation behavior but altered metabolism in neonatal and prepubertal mice.Metabolic characteristics of long-lived mice.Growth Hormone Receptor Antagonist Transgenic Mice Have Increased Subcutaneous Adipose Tissue Mass, Altered Glucose Homeostasis and No Change in White Adipose Tissue Cellular SenescenceThe role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted miceThe effects of weight cycling on lifespan in male C57BL/6J mice.Estrogens regulate the hepatic effects of growth hormone, a hormonal interplay with multiple fates.Upregulation of the angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptor axis in the heart and the kidney of growth hormone receptor knock-out mice.Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice.Mouse models of growth hormone action and aging: a proteomic perspectiveAdiponectin in mice with altered GH action: links to insulin sensitivity and longevity?Growth hormone is a cellular senescence target in pituitary and nonpituitary cellsThe influence of estrogens on the biological and therapeutic actions of growth hormone in the liver.Somatotropic signaling: trade-offs between growth, reproductive development, and longevityAge-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice.
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P2860
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@ast
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@en
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@nl
type
label
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@ast
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@en
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@nl
prefLabel
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@ast
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@en
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@nl
P2093
P2860
P356
P1433
P1476
Endocrine parameters and pheno ...... gene disrupted (GHR-/-) mouse
@en
P2093
Bruce Kelder
Darlene E Berryman
Diana Cruz-Topete
Edward O List
Elahu S Gosney
John J Kopchick
Kevin Funk
Lucila Sackmann-Sala
Shigeru Okada
P2860
P304
P356
10.1210/ER.2010-0009
P407
P577
2011-06-01T00:00:00Z