Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages
about
Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteinsCholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363Macrophage-mediated cholesterol handling in atherosclerosisTranscriptome Profiling Reveals Disruption of Innate Immunity in Chronic Heavy Ethanol Consuming Female Rhesus MacaquesArylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cellsNovel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilizationChemical screen to reduce sterol accumulation in Niemann-Pick C disease cells identifies novel lysosomal acid lipase inhibitors.Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence.Macrophage cholesteryl ester mobilization and atherosclerosisLipid droplets: size matters.Early steps in steroidogenesis: intracellular cholesterol trafficking.Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophagesHuman genome-wide RNAi screen for host factors that modulate intracellular Salmonella growth.The metabolic serine hydrolases and their functions in mammalian physiology and disease.Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol fluxActive autophagy but not lipophagy in macrophages with defective lipolysis.Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis.Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches.Genetics of cholesterol efflux.Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism.Automated quantitative analysis of lipid accumulation and hydrolysis in living macrophages with label-free imaging.Carboxylesterases in lipid metabolism: from mouse to human.A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis.Targeting cholesterol homeostasis in lung diseases.Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics.Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages.Intermittent hypoxia induces murine macrophage foam cell formation by IKK-β-dependent NF-κB pathway activation.Neutral cholesterol ester hydrolases in macrophages: still a matter of debate.NCEH-1 modulates cholesterol metabolism and protects against α-synuclein toxicity in a C. elegans model of Parkinson's disease.An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells.NCEH1 hydrolyzes cholesterol estersMechanisms of foam cell formation in atherosclerosis.
P2860
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P2860
Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Identification of neutral chol ...... g cholesterol from macrophages
@ast
Identification of neutral chol ...... g cholesterol from macrophages
@en
Identification of neutral chol ...... g cholesterol from macrophages
@nl
type
label
Identification of neutral chol ...... g cholesterol from macrophages
@ast
Identification of neutral chol ...... g cholesterol from macrophages
@en
Identification of neutral chol ...... g cholesterol from macrophages
@nl
prefLabel
Identification of neutral chol ...... g cholesterol from macrophages
@ast
Identification of neutral chol ...... g cholesterol from macrophages
@en
Identification of neutral chol ...... g cholesterol from macrophages
@nl
P2093
P2860
P3181
P356
P1476
Identification of neutral chol ...... g cholesterol from macrophages
@en
P2093
Hiroaki Okazaki
Jun-ichi Osuga
Keisuke Ohta
Ken Ohashi
Makiko Nishi
Makiko Tajima
Masaki Igarashi
Michiyo Amemiya-Kudo
Mikio Takanashi
Motohiro Sekiya
P2860
P304
P3181
P356
10.1074/JBC.M802686200
P407
P577
2008-11-28T00:00:00Z