Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions - Wikidata - awgldk - TriplyDB

Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

http://www.wikidata.org/entity/Q24651528

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Nedd4-2 and the regulation of epithelial sodium transport The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration The histone deacetylase SIRT2 stabilizes Myc oncoproteins Respiratory distress and perinatal lethality in Nedd4-2-deficient mice Regulation of trafficking of activated TrkA is critical for NGF-mediated functions Serum and Glucocorticoid Regulated Kinase 1 in Sodium Homeostasis Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling NEDD4: a promising target for cancer therapy A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis.Adhesion to carbon nanotube conductive scaffolds forces action-potential appearance in immature rat spinal neurons Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32 Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting Conditionally disordered proteins: bringing the environment back into the fold.Endocytic regulation of alkali metal transport proteins in mammals, yeast and plants.Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s.Identification of Nedd4 E3 ubiquitin ligase as a binding partner and regulator of MAK-V protein kinase.Nedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons.The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice.Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1 The short isoform of the ubiquitin ligase NEDD4L is a CREB target gene in hepatocytes.Microarray analysis of perinatal-estrogen-induced changes in gene expression related to brain sexual differentiation in mice.Differential gene expression of cardiac ion channels in human dilated cardiomyopathy.NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.Drosophila Ndfip is a novel regulator of Notch signaling.USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2.Enhanced expression of epithelial sodium channels causes salt-induced hypertension in mice through inhibition of the α2-isoform of Na+, K+-ATPase Silencing of PMEPA1 accelerates the growth of prostate cancer cells through AR, NEDD4 and PTEN.Cardiac Nav 1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6.NEDD4 Regulates PAX7 Levels Promoting Activation of the Differentiation Program in Skeletal Muscle Precursors.Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.The copper transporter 1 (CTR1) is required to maintain the stability of copper transporter 2 (CTR2).Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.

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P2860

Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

http://www.wikidata.org/entity/Q24651528

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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type

label

Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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prefLabel

Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

@ast

Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

@en

Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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Cell Death & Differentiation

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Nedd4 and Nedd4-2: closely rel ...... stinct physiological functions

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B Yang

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P2860

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

Ubiquitination regulates PTEN nuclear import and tumor suppression

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2

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scholarly article

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10.1038/CDD.2009.84

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1

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17

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1051564387

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19557014

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