Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans
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Lessons from C. elegans: signaling pathways for longevityUsing Caenorhabditis elegans to Uncover Conserved Functions of Omega-3 and Omega-6 Fatty AcidsPhysiological control of germline developmentDAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegansGermline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegansA novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevityA functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegansDietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegansFluorodeoxyuridine improves Caenorhabditis elegans proteostasis independent of reproduction onsetGenome-wide analysis of germline signaling genes regulating longevity and innate immunity in the nematode Pristionchus pacificusMediation of organismal aging and somatic proteostasis by the germlineA steroid receptor-microRNA switch regulates life span in response to signals from the gonadGain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally DistinctMetabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegansAlternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Cytochrome b5 reductase and the control of lipid metabolism and healthspan.Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling.Lipid profiles of female and male DrosophilaCaenorhabditis elegans metabolic gene regulatory networks govern the cellular economy.Mulberry leaf polyphenols delay aging and regulate fat metabolism via the germline signaling pathway in Caenorhabditis elegansAging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.AMPK at the nexus of energetics and aging.New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals.Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging.Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.The mysterious relationship between reproduction and longevity.Vitellogenin-RNAi and ovariectomy each increase lifespan, increase protein storage, and decrease feeding, but are not additive in grasshoppers.Transcriptional analysis reveals a high impact of conjugated linoleic acid on stearoyl-Coenzyme A desaturase 1 mRNA expression in mice gastrocnemius muscle.Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7.Stress response pathways protect germ cells from omega-6 polyunsaturated fatty acid-mediated toxicity in Caenorhabditis elegans.Reproduction, fat metabolism, and life span: what is the connection?Regulation of longevity by the reproductive system.Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signalsNuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations.Autophagy-mediated longevity is modulated by lipoprotein biogenesis.Roles for ROS and hydrogen sulfide in the longevity response to germline loss in Caenorhabditis elegans.Life-extending ovariectomy in grasshoppers increases somatic storage, but dietary restriction with an equivalent feeding rate does notC30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans.
P2860
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P2860
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@ast
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@en
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@nl
type
label
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@ast
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@en
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@nl
prefLabel
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@ast
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@en
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@nl
P2093
P2860
P3181
P1433
P1476
Fatty acid desaturation links ...... ough NHR-80/HNF4 in C. elegans
@en
P2093
Esther Toselli-Mollereau
Hugo Aguilaniu
Jérôme Goudeau
Mehrnaz Shamalnasab
Stéphanie Bellemin
Yiqun Chen
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1000599
P407
P577
2011-03-01T00:00:00Z