Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
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Diversity and modularity of G protein-coupled receptor structuresLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesNew insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptorsTargeting of Drosophila rhodopsin requires helix 8 but not the distal C-terminusG-protein-coupled receptor inactivation by an allosteric inverse-agonist antibodyUnderstanding functional residues of the cannabinoid CB1.Structural approaches to understanding retinal proteins needed for visionThe role of gene duplication and unconstrained selective pressures in the melanopsin gene family evolution and vertebrate circadian rhythm regulationMolecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes.Characterizing and predicting the functional and conformational diversity of seven-transmembrane proteins.Model of the complex of Parathyroid hormone-2 receptor and Tuberoinfundibular peptide of 39 residuesComparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase.Photochemistry of visual pigment in a G(q) protein-coupled receptor (GPCR)--insights from structural and spectral tuning studies on squid rhodopsin.Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?Drawing the Retinal Out of Its Comfort Zone: An ONIOM(QM/MM) Study of Mutant Squid Rhodopsin.GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models.Collation and data-mining of literature bioactivity data for drug discovery.Action of molecular switches in GPCRs--theoretical and experimental studies.QM/MM study of dehydro and dihydro β-ionone retinal analogues in squid and bovine rhodopsins: implications for vision in salamander rhodopsin.Conservation of molecular interactions stabilizing bovine and mouse rhodopsin.The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.QM/MM study of the structure, energy storage, and origin of the bathochromic shift in vertebrate and invertebrate bathorhodopsins.Discovery of new GPCR biology: one receptor structure at a time.Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptorProgress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.The significance of G protein-coupled receptor crystallography for drug discovery.Methodology of pulsed photoacoustics and its application to probe photosystems and receptors.Homology modeling of class a G protein-coupled receptorsPreparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin.Differential Virtual Screening (DVS) with Active and Inactive Molecular Models for Finding and Profiling GPCR Modulators: Case of the CCK1 Receptor.Transmembrane helix: simple or complex.A Strategy Combining Differential Low-Throughput Screening and Virtual Screening (DLS-VS) Accelerating the Discovery of new Modulators for the Orphan GPR34 Receptor.From atomic structures to neuronal functions of g protein-coupled receptorsStructural differences and differential expression among rhabdomeric opsins reveal functional change after gene duplication in the bay scallop, Argopecten irradians (Pectinidae).Optogenetic interrogation reveals separable G-protein-dependent and -independent signalling linking G-protein-coupled receptors to the circadian oscillator.Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.GPCR activation: protonation and membrane potentialThe effect of ligand efficacy on the formation and stability of a GPCR-G protein complex.
P2860
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P2860
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@ast
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@en
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@nl
type
label
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@ast
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@en
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@nl
prefLabel
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@ast
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@en
Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region
@nl
P2093
P2860
P356
P1476
Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region
@en
P2093
Katsuyoshi Masuda
Kenji Hiraki
Koji Takio
Masaji Ishiguro
Masashi Miyano
Naoko Takahashi
Tatsuro Shimamura
Tetsuya Hori
P2860
P304
17753-17756
P356
10.1074/JBC.C800040200
P407
P50
P577
2008-05-06T00:00:00Z