Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1 - Wikidata - awgldk - TriplyDB

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

http://www.wikidata.org/entity/Q27651005

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Regulation of small GTPases by GEFs, GAPs, and GDIs Vav family exchange factors: an integrated regulatory and functional view Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1 Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2 Developing advanced X-ray scattering methods combined with crystallography and computation The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity.Mechanism and function of Vav1 localisation in TCR signalling.Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering.Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase Molecular basis for failure of "atypical" C1 domain of Vav1 to bind diacylglycerol/phorbol ester.The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.Function of the nucleotide exchange activity of vav1 in T cell development and activation.Vav1 GEF activity is required for T cell mediated allograft rejection Altered function of monocytes/macrophages in patients with autoimmune hepatitis.Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae.Discovery and characterization of small molecule Rac1 inhibitors The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.A Novel Vav3 Homolog Identified in Lamprey, Lampetra japonica, with Roles in Lipopolysaccharide-Mediated Immune Response.c-Abl tyrosine kinase regulates neutrophil crawling behavior under fluid shear stress via Rac/PAK/LIMK/cofilin signaling axis.VAV1 is a GEF for Rho/Rac family kinases VAV2 is a GEF for Rho/Rac family kinases VAV3 is a GEF for Rho/Rac family kinases

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P2860

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

http://www.wikidata.org/entity/Q27651005

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

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J.JMB.2008.05.024

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Journal of Molecular Biology

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Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1

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Alexei Brooun

http://www.w3.org/2001/XMLSchema#string

Gary M Bokoch

http://www.w3.org/2001/XMLSchema#string

Gisbert Weckbecker

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Greg L Hura

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Hans Widmer

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Hui Zhang

http://www.w3.org/2001/XMLSchema#string

Irimpan I Mathews

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J Jefferson P Perry

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Jill E Chrencik

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Markus Streiff

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P2860

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.

vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle

Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation

Determination of domain structure of proteins from X-ray solution scattering

The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site

The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activation

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

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828-843

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scholarly article

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10.1016/J.JMB.2008.05.024

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5

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380

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2008-05-17T00:00:00Z

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5263065

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18589439

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2620086

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