Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3- d ]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents
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Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitorsFirst Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase–Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate ChannelingAn innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymesAntifolate agents: a patent review (2006 - 2010).New antibacterials for the treatment of toxoplasmosis; a patent review.Synthesis, Biological Evaluation and Molecular Docking Studies of 6-Aryl-2-Styrylquinazolin-4(3H)-Ones.2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition.Proteochemometric Modeling of the Origin of Thymidylate Synthase Inhibition.Design, Synthesis, and Biological Activity of Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Anti-Inflammatory Agents.Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities.
P2860
Q27667755-7A000C24-A25B-4590-818E-9D2E8AB38DB3Q27680002-08D3A37E-7A1B-4174-A95B-58CC31BDC3BEQ28486030-4A92F149-F6C8-4C19-BD48-45FCEC7C3DE5Q34187926-4C42425C-6AB6-469D-A875-088B6B46336BQ37992089-92CAFEC3-FF9A-4834-BE0B-A509FA6BE6F7Q38808329-99D2AAB4-ABE3-4A21-AF1C-D60F4F273BE1Q39807158-34F7FC52-8037-44A1-9717-1B4E11F879F8Q46237610-29F771C7-EA36-40D0-84F3-EF9B74679A5CQ47403944-790BD976-6529-4E6A-9D39-075AFB9DA4DAQ47614531-0DFB584D-D8CB-421F-BE6B-36EDBDA7194E
P2860
Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3- d ]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents
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2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
type
label
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
prefLabel
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
P2093
P2860
P921
P356
P1476
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
P2093
Aleem Gangjee
Jennifer Makin
Jennifer Piraino
Roy L Kisliuk
Vivian Cody
P2860
P304
P356
10.1021/JM900490A
P407
P577
2009-08-13T00:00:00Z