Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3- d ]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3- d ]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents

Item
http://www.wikidata.org/entity/Q27657240
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitorsFirst Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase–Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate ChannelingAn innovative strategy for dual inhibitor design and its application in dual inhibition of human thymidylate synthase and dihydrofolate reductase enzymesAntifolate agents: a patent review (2006 - 2010).New antibacterials for the treatment of toxoplasmosis; a patent review.Synthesis, Biological Evaluation and Molecular Docking Studies of 6-Aryl-2-Styrylquinazolin-4(3H)-Ones.2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition.Proteochemometric Modeling of the Origin of Thymidylate Synthase Inhibition.Design, Synthesis, and Biological Activity of Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Anti-Inflammatory Agents.Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities.
P2860

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno[2,3- d ]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents

Item
http://www.wikidata.org/entity/Q27657240
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
type
label
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
prefLabel
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@ast
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
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P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Design, Synthesis, and X-ray C ...... as Potential Antitumor Agents
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932