Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain

Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain

Item
http://www.wikidata.org/entity/Q27664909
3D models of MBP, a biologically active metabolite of bisphenol A, in human estrogen receptor α and estrogen receptor βSurvey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data.An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist positionDiosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.Versatility or promiscuity: the estrogen receptors, control of ligand selectivity and an update on subtype selective ligands.Estrogen receptor α/β-cofactor motif interactions; interplay of tyrosine 537/488 phosphorylation and LXXLL motifs.Phosphorylation of the retinoic acid receptor alpha induces a mechanical allosteric regulation and changes in internal dynamics.Structural characterization of the binding interactions of various endogenous estrogen metabolites with human estrogen receptor α and β subtypes: a molecular modeling study.Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.The dynamic structure of the estrogen receptorEcdysteroids: A novel class of anabolic agents?A structural perspective on nuclear receptors as targets of environmental compounds.Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development.Target of rapamycin FATC domain as a general membrane anchor: The FKBP-12 like domain of FKBP38 as a case study.Phytoestrogenic Activity of Blackcurrant Anthocyanins Is Partially Mediated through Estrogen Receptor Beta.ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models.
P2860

Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain

Item
http://www.wikidata.org/entity/Q27664909
description
2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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name
Synthesis and crystal structur ...... receptor ligand binding domain
@ast
Synthesis and crystal structur ...... receptor ligand binding domain
@en
Synthesis and crystal structur ...... receptor ligand binding domain
@nl
type
label
Synthesis and crystal structur ...... receptor ligand binding domain
@ast
Synthesis and crystal structur ...... receptor ligand binding domain
@en
Synthesis and crystal structur ...... receptor ligand binding domain
@nl
prefLabel
Synthesis and crystal structur ...... receptor ligand binding domain
@ast
Synthesis and crystal structur ...... receptor ligand binding domain
@en
Synthesis and crystal structur ...... receptor ligand binding domain
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Synthesis and crystal structur ...... receptor ligand binding domain
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P921