Thienopyrimidine bisphosphonate (ThPBP) inhibitors of the human farnesyl pyrophosphate synthase: optimization and characterization of the mode of inhibition
about
Human isoprenoid synthase enzymes as therapeutic targetsSynthetic Procedures Leading towards AminobisphosphonatesDrug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase.Solvent effect on molecular structure, IR spectra, thermodynamic properties and chemical stability of zoledronic acid: DFT study.Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product.3D-QSAR, molecular docking, and ONIOM studies on the structure-activity relationships and action mechanism of nitrogen-containing bisphosphonates.
P2860
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P2860
Thienopyrimidine bisphosphonate (ThPBP) inhibitors of the human farnesyl pyrophosphate synthase: optimization and characterization of the mode of inhibition
description
2013 nî lūn-bûn
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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@ast
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@en
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@nl
type
label
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@ast
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@en
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@nl
prefLabel
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@ast
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@en
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@nl
P2093
P356
P1476
Thienopyrimidine bisphosphonat ...... tion of the mode of inhibition
@en
P2093
Chun Yuen Leung
Joris W De Schutter
Michael Sebag
Youla S Tsantrizos
P304
P356
10.1021/JM400946F
P407
P577
2013-10-03T00:00:00Z