Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease
about
Crystal structure of the BTB domain from PLZFPredicting deleterious amino acid substitutionsChemical synthesis of proteinsKnowledge-based model building of proteins: concepts and examplesRetroviral proteasesImproved prediction of HIV-1 protease-inhibitor binding energies by molecular dynamics simulationsRole of Marine Natural Products in the Genesis of Antiviral AgentsA brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruitsFoamy virus assembly with emphasis on pol encapsidationIn silico prediction of mutant HIV-1 proteases cleaving a target sequenceActive residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virusAn antibody- and synthetic peptide-defined rubella virus E1 glycoprotein neutralization domainThe Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PRThe crystal structure and mechanism of 1-L-myo-inositol- 1-phosphate synthaseViability of a drug-resistant human immunodeficiency virus type 1 protease variant: structural insights for better antiviral therapySolution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursorDirect observation by X-ray analysis of the tetrahedral “intermediate” of aspartic proteinasesNucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modelingCaught in the Act: The 1.5 Å Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate †Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 ProteaseInvolvement of Water in Carbohydrate−Protein Binding: Concanavalin A RevisitedCrystal Structures of the Histo-Aspartic Protease (HAP) from Plasmodium falciparumStructure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypesProbing Multidrug-Resistance and Protein-Ligand Interactions with Oxatricyclic Designed Ligands in HIV-1 Protease InhibitorsCrystal structure of XMRV protease differs from the structures of other retropepsinsContribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variantsStructural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus proteaseProtein conformational dynamics in the mechanism of HIV-1 protease catalysisThe Cyclic Cystine Ladder in -Defensins Is Important for Structure and Stability, but Not Antibacterial ActivitySynthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease InhibitorsHIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural RearrangementsX-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitorJoint X-ray/Neutron Crystallographic Study of HIV-1 Protease with Clinical Inhibitor Amprenavir: Insights for Drug DesignTotal chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humansX-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsinStructural Maturation of HIV-1 Reverse Transcriptase-A Metamorphic Solution to Genomic InstabilityThe aspartic proteases
P2860
Q22003945-976DC49C-0048-4A9D-94E2-B7C831DC6E1AQ22065761-F64E4D36-3CAB-491E-BF6C-09FDAC0214FBQ24613703-F29C7C36-13A2-45C7-A3B5-19FCB9952358Q24676038-484918B0-8EB6-4A7D-8584-BD721EF592D4Q24791668-12EAB862-9A4F-466D-AAB8-E467BFCC5C0DQ24794072-9BB78600-3406-49A0-955F-373373E1770AQ26796360-CB7AB933-FA03-4717-8AE6-6F77A0D65797Q26823889-0C4403FB-1EBC-47E3-BBED-68D3594654EFQ26860084-6B0ACDED-95AC-4C30-AE9B-6AD7A60084BCQ27335448-C71C822E-3DBE-49EF-A545-D30C0FBE5672Q27469635-F824382E-C7D8-472D-A075-F60047E43F7AQ27486019-1890D479-3071-4D2F-874B-80D345C8D708Q27489856-58E2D7CC-ECE8-4A92-A60F-0649E75A0F95Q27629375-AF61C841-87B9-4A9C-9B28-A495C2A5AA8CQ27637191-1AA600D3-9A6B-4282-844F-2AA0E422FA36Q27640250-82B3471F-040D-4AAF-AF36-A82E7A8F9934Q27641889-F4B545DC-3232-4FC9-B5B1-6D26649BB71DQ27642040-23833506-FE1B-45D6-B306-47A77100A423Q27642042-BBD94461-D8BD-4C86-9742-B0C4DF9EBAB5Q27642043-A2AC8A49-B32A-4226-A858-55992D9F2E15Q27649183-275D7B2A-5C5D-4511-81FA-DA32E1406D18Q27649876-EBD35A93-6093-462A-AD4B-545C13B5AD3BQ27653045-C869E24A-09F5-4763-AD86-F4BA1F24007EQ27654096-B479832E-94DD-4A16-872E-718222D0B037Q27660028-A56B2BD4-F859-4000-9335-32F1E07C7318Q27664394-C2B3B988-080F-477B-9E47-760DEDF2F343Q27666692-8B187FD7-BDA8-4046-8235-3665E2F886EAQ27668148-D0B952BA-3CAD-4B27-AEFD-50C0B0051929Q27674531-F2DBD315-637E-42BD-8302-FA1C07DDC628Q27676129-93CEF319-73CA-4B3D-9F8C-7C249FCAD9BBQ27676502-CC18FE78-222A-4BC8-9AC9-5E96BCB60E42Q27677537-FF0913E3-BBEE-452B-ABDC-DE35E5FFDAB6Q27677952-8E98753A-1389-4D43-B7D1-706B6B4C09B9Q27678325-AA361A6C-0092-41C1-BA29-36860B7C1555Q27678644-CC6C991F-DD41-4954-9869-9A7980E71FB7Q27728121-BA111089-84A6-4032-A3B4-322CFCFFD547Q27729982-93515670-3BCA-465C-869F-F8D82F1B7085Q27732078-00FBA1F3-0216-4183-8AAE-559766372E9FQ28074527-908F8BB1-C65A-4CAF-AFF7-6EDF65386E07Q28208915-86D57722-C619-41E4-A6BF-9F13436CDABE
P2860
Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease
description
1989 nî lūn-bûn
@nan
1989 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@ast
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@en
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@nl
type
label
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@ast
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@en
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@nl
prefLabel
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@ast
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@en
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@nl
P2093
P3181
P356
P1433
P1476
Conserved folding in retrovira ...... of a synthetic HIV-1 protease
@en
P2093
A Wlodawer
B K Sathyanarayana
J Schneider
M Jaskólski
P304
P3181
P356
10.1126/SCIENCE.2548279
P407
P50
P577
1989-08-11T00:00:00Z