Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
about
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interferenceSilencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsGenome stability is ensured by temporal control of kinetochore-microtubule dynamicsCell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cellsA mitotic septin scaffold required for Mammalian chromosome congression and segregationRegulation of localization and activity of the microtubule depolymerase MCAKTowards a quantitative understanding of mitotic spindle assembly and mechanicsThe centromere geometry essential for keeping mitosis error free is controlled by spindle forcesBorealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindleThe KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAKThe kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingThe KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegansThe far C-terminus of MCAK regulates its conformation and spindle pole focusing.A second tubulin binding site on the kinesin-13 motor head domain is important during mitosisTTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylationKLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection forceLateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKKinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerasesSequential assembly of centromeric proteins in male mouse meiosisA Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning PredictionsThe expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear rolesICIS and Aurora B coregulate the microtubule depolymerase Kif2aAurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its functionThe condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosisThe influence of chromosome flexibility on chromosome transport during anaphase A.Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis.Deciphering protein function during mitosis in PtK cells using RNAi.Chromosome malorientations after meiosis II arrest cause nondisjunctionExamining the link between chromosomal instability and aneuploidy in human cellsThe spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement.Mechanisms of chromosome behaviour during mitosisKinetochores use a novel mechanism for coordinating the dynamics of individual microtubules.Kif18B interacts with EB1 and controls astral microtubule length during mitosis.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.
P2860
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P2860
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Depletion of centromeric MCAK ...... proper kinetochore attachments
@ast
Depletion of centromeric MCAK ...... proper kinetochore attachments
@en
Depletion of centromeric MCAK ...... proper kinetochore attachments
@nl
type
label
Depletion of centromeric MCAK ...... proper kinetochore attachments
@ast
Depletion of centromeric MCAK ...... proper kinetochore attachments
@en
Depletion of centromeric MCAK ...... proper kinetochore attachments
@nl
prefLabel
Depletion of centromeric MCAK ...... proper kinetochore attachments
@ast
Depletion of centromeric MCAK ...... proper kinetochore attachments
@en
Depletion of centromeric MCAK ...... proper kinetochore attachments
@nl
P2093
P2860
P3181
P356
P1476
Depletion of centromeric MCAK ...... proper kinetochore attachments
@en
P2093
Alexey Khodjakov
Claire E Walczak
Polla Hergert
Susan L Kline-Smith
P2860
P304
P3181
P356
10.1091/MBC.E03-08-0581
P407
P577
2003-12-29T00:00:00Z