Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments - Wikidata - awgldk - TriplyDB

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

http://www.wikidata.org/entity/Q28236606

about

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments Genome stability is ensured by temporal control of kinetochore-microtubule dynamics Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells A mitotic septin scaffold required for Mammalian chromosome congression and segregation Regulation of localization and activity of the microtubule depolymerase MCAK Towards a quantitative understanding of mitotic spindle assembly and mechanics The centromere geometry essential for keeping mitosis error free is controlled by spindle forces Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling The KLP-7 Residue S546 Is a Putative Aurora Kinase Site Required for Microtubule Regulation at the Centrosome in C. elegans The far C-terminus of MCAK regulates its conformation and spindle pole focusing.A second tubulin binding site on the kinesin-13 motor head domain is important during mitosis TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation KLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases Sequential assembly of centromeric proteins in male mouse meiosis A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles ICIS and Aurora B coregulate the microtubule depolymerase Kif2a Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function The condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosis The influence of chromosome flexibility on chromosome transport during anaphase A.Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis.Deciphering protein function during mitosis in PtK cells using RNAi.Chromosome malorientations after meiosis II arrest cause nondisjunction Examining the link between chromosomal instability and aneuploidy in human cells The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics.The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement.Mechanisms of chromosome behaviour during mitosis Kinetochores use a novel mechanism for coordinating the dynamics of individual microtubules.Kif18B interacts with EB1 and controls astral microtubule length during mitosis.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.

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Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

http://www.wikidata.org/entity/Q28236606

description

2003 nî lūn-bûn

@nan

2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Depletion of centromeric MCAK ...... proper kinetochore attachments

@ast

Depletion of centromeric MCAK ...... proper kinetochore attachments

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Depletion of centromeric MCAK ...... proper kinetochore attachments

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type

label

Depletion of centromeric MCAK ...... proper kinetochore attachments

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Depletion of centromeric MCAK ...... proper kinetochore attachments

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Depletion of centromeric MCAK ...... proper kinetochore attachments

@nl

prefLabel

Depletion of centromeric MCAK ...... proper kinetochore attachments

@ast

Depletion of centromeric MCAK ...... proper kinetochore attachments

@en

Depletion of centromeric MCAK ...... proper kinetochore attachments

@nl

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MBC.E03-08-0581

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Molecular Biology of the Cell

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Depletion of centromeric MCAK ...... proper kinetochore attachments

@en

P2093

Alexey Khodjakov

http://www.w3.org/2001/XMLSchema#string

Claire E Walczak

http://www.w3.org/2001/XMLSchema#string

Polla Hergert

http://www.w3.org/2001/XMLSchema#string

Susan L Kline-Smith

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P2860

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis

How cells get the right chromosomes

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1146-1159

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scholarly article

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3907238

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10.1091/MBC.E03-08-0581

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3

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15

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2003-12-29T00:00:00Z

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8939381

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14699064

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363095

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