Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer - Wikidata - awgldk - TriplyDB

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

http://www.wikidata.org/entity/Q28242111

about

Epigenetic field defects in progression to cancer Mutator pathways unleashed by epigenetic silencing in human cancer Epigenetic changes of DNA repair genes in cancer Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology Roles of Werner syndrome protein in protection of genome integrity Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene Human premature aging, DNA repair and RecQ helicases Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer Common features of chromatin in aging and cancer: cause or coincidence?Crystal structure of the HRDC domain of human Werner syndrome protein, WRN Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease Epigenetic reduction of DNA repair in progression to gastrointestinal cancer Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer The Werner's Syndrome RecQ helicase/exonuclease at the nexus of cancer and aging Genomic aberrations in lung adenocarcinoma in never smokers PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast Cancer CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.Expression of (NES-)hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stress DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.Candidate biomarkers for cervical cancer treatment: Potential for clinical practice (Review).What would you do if you could sequence everything?DNA methyltransferases, DNA damage repair, and cancer MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.Comparison of proliferation and genomic instability responses to WRN silencing in hematopoietic HL60 and TK6 cells.Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer Epigenetic gene silencing in cancer: the DNA hypermethylome.Roles of the Werner syndrome RecQ helicase in DNA replication.RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.Systematic genomic identification of colorectal cancer genes delineating advanced from early clinical stage and metastasis DAMPs, ageing, and cancer: The 'DAMP Hypothesis'.A seven-gene CpG-island methylation panel predicts breast cancer progression The genetics and epigenetics of altered proliferative homeostasis in ageing and cancer Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design Aging genetics and aging.

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

http://www.wikidata.org/entity/Q28242111

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

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name

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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type

label

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

@en

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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prefLabel

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

@en

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

@nl

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PNAS.0600645103

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Proceedings of the National Academy of Sciences of the United States of America

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

@en

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Cayetano von Kobbe

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David Guerrero

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Fernando Setien

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Maria F Paz

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Mario F Fraga

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Michel Herranz

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Ruben Agrelo

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Santiago Ropero

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Vilhelm A Bohr

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Wen-Hsing Cheng

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P2860

Werner Syndrome

p53 Modulates the exonuclease activity of Werner syndrome protein

The Werner syndrome protein is a DNA helicase

p53-mediated apoptosis is attenuated in Werner syndrome cells

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

LMNA mutations in atypical Werner's syndrome

Werner syndrome: genetic and molecular basis of a premature aging disorder

Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers

Methylation matters

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

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23

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103

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Antoni Castells

Montse Sanchez-Cespedes

Maria-Jesus Artiga

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2006-05-24T00:00:00Z

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7060227

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16723399

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1466544

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