The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling
about
Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue CattleEndosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassemblyProstate cancer relevant antigens and enzymes for targeted drug deliveryPeptide Length and Leaving-Group Sterics Influence Potency of Peptide Phosphonate Protease InhibitorsuPARAP function in cutaneous wound repairInhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library.A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion.Membranous nephropathy: from models to manMRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma.Extracellular proteases as targets for drug developmentUrokinase and its receptors in chronic kidney disease.The non-phagocytic route of collagen uptake: a distinct degradation pathway.A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice.Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast DifferentiationMannose receptor 2 attenuates renal fibrosisRole of urokinase plasminogen activator receptor-associated protein in mouse lungInhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo.Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy.Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice.Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells.Involvement of fibrocytes in asthma and clinical implications.Hepatitis B virus inhibits liver regeneration via epigenetic regulation of urokinase-type plasminogen activator.Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180.A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor.CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene.A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth.uPARAP expression during murine lung development.Challenges for drug discovery - a case study of urokinase receptor inhibitionExpression of Endo180 is spatially and temporally regulated during wound healing.Effect of surface charge and ligand organization on the specific cell-uptake of uPAR-targeted nanoparticles.Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.Matrix Proteases and the DegradomeTargeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180
P2860
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P2860
The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@ast
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@en
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@nl
type
label
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@ast
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@en
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@nl
prefLabel
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@ast
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@en
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@nl
P2860
P356
P1433
P1476
The urokinase receptor (uPAR) ...... nover during tissue remodeling
@en
P2093
Niels Behrendt
P2860
P304
P356
10.1515/BC.2004.031
P407
P577
2004-02-01T00:00:00Z