Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling - Wikidata - awgldk - TriplyDB

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

http://www.wikidata.org/entity/Q28268458

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Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor hSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathways Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF The elucidation of novel SH2 binding sites on PLD2 Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction Activation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5 SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells A Ras-GTPase-activating protein SH3-domain-binding protein Bivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative manner Subsets of epidermal growth factor receptors during activation and endocytosis Differential interactions of human Sos1 and Sos2 with Grb2 NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1 The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2 The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway Regulation of Sos activity by intramolecular interactions.A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas The human GRB2 and Drosophila Drk genes can functionally replace the Caenorhabditis elegans cell signaling gene sem-5.Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase.N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains The structure and function of proline-rich regions in proteins The beta-subunit of the hepatocyte growth factor/scatter factor (HGF/SF) receptor phosphorylates and associates with CrkII: expression of CrkII enhances HGF/SF-induced mitogenesis Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

http://www.wikidata.org/entity/Q28268458

description

1993 nî lūn-bûn

@nan

1993 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1993 թվականի մայիսին հրատարակված գիտական հոդված

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1993年の論文

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1993年論文

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1993年論文

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1993年論文

@zh-hk

1993年論文

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1993年論文

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1993年论文

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name

Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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type

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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prefLabel

Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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Guanine-nucleotide-releasing f ...... sine kinases to Ras signalling

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A Batzer

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B Margolis

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D Bar-Sagi

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E Skolnik

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J Schlessinger

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N Li

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P Chardin

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R Daly

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V Yajnik

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85-8

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scholarly article

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1905840

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10.1038/363085A0

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6424

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363

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1011022170

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8479541

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