mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
about
Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAsPHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growthThe mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activityTSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translationmTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptideThe crosstalk of mTOR/S6K1 and Hedgehog pathwaysReconstitution reveals the functional core of mammalian eIF3The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophyControl of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase14-3-3 interacts with LKB1 via recognizing phosphorylated threonine 336 residue and suppresses LKB1 kinase functionmTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyMammalian target of rapamycin (mTOR): conducting the cellular signaling symphonymTOR: from growth signal integration to cancer, diabetes and ageingRegulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylationTranslational control by a small RNA: dendritic BC1 RNA targets the eukaryotic initiation factor 4A helicase mechanismSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsMechanical Signaling in the Pathophysiology of Critical Illness MyopathyRegulation of global and specific mRNA translation by the mTOR signaling pathwayMilk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent TranslationHomeostatic plasticity at the Drosophila neuromuscular junction'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsAutophagy is essential to support skeletal muscle plasticity in response to endurance exercisemTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsThe translational factor eIF3f: the ambivalent eIF3 subunitThe regulation of the autophagic network and its implications for human diseaseThe expanding role of mTOR in cancer cell growth and proliferationCrystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motifMetabolic benefits of resistance training and fast glycolytic skeletal muscle.mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesiaThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsRegulation of translation initiation in eukaryotes: mechanisms and biological targetseIF3 targets cell-proliferation messenger RNAs for translational activation or repressionLa-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksEffect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activityQuantitative studies of mRNA recruitment to the eukaryotic ribosome
P2860
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P2860
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@ast
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@en
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@nl
type
label
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@ast
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@en
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@nl
prefLabel
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@ast
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@en
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@nl
P2093
P3181
P1433
P1476
mTOR and S6K1 mediate assembly ...... ordered phosphorylation events
@en
P2093
Bryan A Ballif
John Blenis
Marina K Holz
P304
P3181
P356
10.1016/J.CELL.2005.10.024
P407
P577
2005-11-18T00:00:00Z