The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
about
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansHeat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophagesDICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88A novel Toll-like receptor that recognizes vesicular stomatitis virusToll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responsesUNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondiiPathogen recognition and inflammatory signaling in innate immune defensesMicrobe sensing, positive feedback loops, and the pathogenesis of inflammatory diseasesCross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsIntracellular nucleic acid sensors and autoimmunityRNA mediated Toll-like receptor stimulation in health and diseaseThe effects of TLR activation on T-cell development and differentiationDissecting immunity by germline mutagenesisTLR9-dependent and independent pathways drive activation of the immune system by Propionibacterium acnesSplenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for controlUNC93B1 mediates host resistance to infection with Toxoplasma gondiiKey role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivoDeterminants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control itAge-dependent enterocyte invasion and microcolony formation by SalmonellaThe Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicingAsparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activationMutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3' splice site in vivoToll-like receptors regulation of viral infection and disease☆The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsThe Role of Toll-Like Receptors in Hematopoietic MalignanciesSexual dimorphism in autoimmunityExploiting host immunity: the Salmonella paradigmMyD88: a central player in innate immune signalingCytoplasmic DNA innate immune pathwaysInnate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responsesJinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosisFlt3 permits survival during infection by rendering dendritic cells competent to activate NK cellsNucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responsesTLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modificationThe interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signalingIgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patientsSystems biology of innate immunityPIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signalingThe ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.
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P2860
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
description
2006 nî lūn-bûn
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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2006 թվականի փետրվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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type
label
The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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prefLabel
The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
@ast
The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
@en
The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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The Unc93b1 mutation 3d disrup ...... Toll-like receptors 3, 7 and 9
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Anat A Herskovits
Benjamin E Steinberg
Daniel A Portnoy
Edith M Janssen
Jason Goode
Lisa M Tarantino
Louis Shamel
Michael Cooke
Navjiwan Mann
Sosathya Sovath
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10.1038/NI1297
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2006-02-01T00:00:00Z
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1011532313