Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
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SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signalingThe neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cellsFamilial syndromes associated with neuroendocrine tumoursEnteric nervous system development: migration, differentiation, and diseaseLower urinary tract development and diseaseGDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson diseaseThe GDNF family: signalling, biological functions and therapeutic valueAll-trans retinoic acid-responsive genes identified in the human SH-SY5Y neuroblastoma cell line and their regulated expression in the nervous system of early embryosMolecular mechanisms of RET-induced Hirschsprung pathogenesisNephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in miceSOX9 controls epithelial branching by activating RET effector genes during kidney developmentDiminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.Vascularisation is not necessary for gut colonisation by enteric neural crest cells.Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase.Kidney development in the absence of Gdnf and Spry1 requires Fgf10.Non-cell-autonomous retinoid signaling is crucial for renal development.Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice.Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis.The transcription factors Etv4 and Etv5 mediate formation of the ureteric bud tip domain during kidney developmentRefining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling.Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud.Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.Advances in ontogeny of the enteric nervous system.Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis.A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-dMitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesionRegion-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance.Alternative splicing in oncogenic kinases: from physiological functions to cancerThe influence of Hox genes and three intercellular signalling pathways on enteric neuromuscular development.Alternative splicing results in RET isoforms with distinct trafficking properties.Mouse models of thyroid cancer: A 2015 update.Structure and physiology of the RET receptor tyrosine kinase.The developmental etiology and pathogenesis of Hirschsprung disease.Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients.Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy.Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia
P2860
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P2860
Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Differential activities of the ...... during mammalian embryogenesis
@ast
Differential activities of the ...... during mammalian embryogenesis
@en
Differential activities of the ...... during mammalian embryogenesis
@nl
type
label
Differential activities of the ...... during mammalian embryogenesis
@ast
Differential activities of the ...... during mammalian embryogenesis
@en
Differential activities of the ...... during mammalian embryogenesis
@nl
prefLabel
Differential activities of the ...... during mammalian embryogenesis
@ast
Differential activities of the ...... during mammalian embryogenesis
@en
Differential activities of the ...... during mammalian embryogenesis
@nl
P2093
P2860
P3181
P356
P1433
P1476
Differential activities of the ...... during mammalian embryogenesis
@en
P2093
B S Mankoo
C Kilkenny
E de Graaff
F Costantini
P2860
P304
P3181
P356
10.1101/GAD.205001
P407
P577
2001-09-15T00:00:00Z