Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
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Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migrationCbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motilityLATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosisProline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activationSemaphorin 4D/plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathwayPyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survivalInterferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytesHic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinaseSuppression of Pyk2 kinase and cellular activities by FIP200West Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of v 3 IntegrinAssociation of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entryThe integrin alpha 7 cytoplasmic domain regulates cell migration, lamellipodia formation, and p130CAS/Crk couplingThe interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and ErkPyk2 and Src mediate signaling to CCL18-induced breast cancer metastasisPTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substratesPlasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitroMonocyte chemoattractant protein 1 causes differential signalling mediated by proline-rich tyrosine kinase 2 in THP-1 cellsEpidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinaseFocal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivoPyk2 regulates multiple signaling events crucial for macrophage morphology and migration.Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migrationFAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophiesFAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression patternPyk2/CAKbeta tyrosine kinase activity-mediated angiogenesis of pulmonary vascular endothelial cellsThe adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signalingConditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesisFocal adhesion kinase: in command and control of cell motilitySRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion.Paxillin: a focal adhesion-associated adaptor protein.The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase.Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase.Regulation of osteoclast structure and function by FAK family kinasesMyocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophyTargeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cellsMechanisms of CAS substrate domain tyrosine phosphorylation by FAK and SrcPaxillin binding is not the sole determinant of focal adhesion localization or dominant-negative activity of focal adhesion kinase/focal adhesion kinase-related nonkinaseThe role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src.Ca2+ lightning conveys cell-cell contact information inside the cells.
P2860
Q22254608-311D0333-E303-401C-BC67-1F81665A3D96Q24290721-E195D28C-FA27-4307-B389-D0F585B4A91EQ24301118-34510685-1B4D-4695-9B36-2CCA18259BD3Q24309608-8210BC74-B60B-48F5-AFA2-1B20D905E9CDQ24311648-8EB28C30-EE65-4B63-A4FD-DE9ED3A014EAQ24313400-D58D9E71-D964-4FE8-B63D-8542BCF7317BQ24535045-D3F80489-C88F-494A-A26C-E44100068F37Q24550885-4E7C4F9E-FB28-4400-AC12-64CF6B059176Q24685945-CF9D169C-F211-4397-89C1-8491C2419A0BQ27486120-6B531031-E68A-4155-9077-52D7A73738EFQ28143730-039C9CDF-851E-4BE1-AE61-9404E4A4FE15Q28208490-AE173A6A-1FD1-4DDA-8C3E-88C003EE0B01Q28243414-F07ABB16-808A-49D9-B529-70B2153B092EQ28300598-2055CDCD-63B3-49B3-ABD7-5CEB2738B06AQ28343311-876C2C8F-E1AD-4560-A1B1-BFABBBE7A064Q28343517-1993590A-62A2-495F-9E43-96CCF062EA2BQ28363253-22E4D073-C412-4C62-B125-859D6FD94926Q28365466-216F8551-A4DF-474B-8FA6-EB5E70FDC94BQ28483939-E62042C7-F7E1-49AA-8EB6-18686CE86636Q28505302-7BF51895-545A-43A7-8408-0ED9649A9D3BQ28505575-91B93130-A4B1-452F-85E5-3CC2F1BAD985Q28511784-7C2BB138-AE67-4A1D-BA9C-1127DC9F2BF7Q28565223-5A567111-DCE8-4990-A0D6-79B5F2510D17Q28582472-2677D7A4-634A-4DEF-9325-682F5747DC55Q28589349-A4D1CB3D-DB0A-4A32-BAE9-642D4826F4EFQ28591107-6D613D00-6C7A-435E-834A-4A590E396085Q29615192-D3A8960F-6EC9-430D-B94C-417444A8D602Q30167497-2C2E0EF1-32AC-4E0C-8B1D-D73FF17A4151Q30167613-9F2907FE-FE0E-4045-B533-318A5056AFC8Q30167845-E87DA44A-A7A6-4C44-AED1-FE902D2983B6Q30168345-B1305D7C-37B3-49D0-B48A-C2942E180341Q30175136-1B00A12D-A2CC-417E-A58A-10BD26688601Q30416629-768F7930-8E4F-4B69-9C1E-5254EE65779EQ30439445-65C8FC3A-0904-4607-BAE2-C65386FCADAFQ30442000-6A39CAA6-368D-4B81-8EEA-E4F379980406Q30453539-1D08E2E2-DFD3-46CB-B4A1-0C44418C3652Q30454453-F883944E-6BBA-4739-AEA2-FABD222E0329Q30476179-5C8D96AC-02B6-4343-9779-E695237A08C1Q30476291-BC92180A-7CF7-49CE-B43C-061D218D7129Q30478421-D5B5B48A-3FE4-453F-BF88-8A1F4EC073EA
P2860
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Pyk2 and Src-family protein-ty ...... to enhance FAK- cell migration
@nl
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@ast
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@en
type
label
Pyk2 and Src-family protein-ty ...... to enhance FAK- cell migration
@nl
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@ast
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@en
prefLabel
Pyk2 and Src-family protein-ty ...... to enhance FAK- cell migration
@nl
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@ast
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@en
P2093
P2860
P3181
P356
P1433
P1476
Pyk2 and Src-family protein-ty ...... o enhance FAK- cell migration.
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/17.20.5933
P407
P577
1998-10-01T00:00:00Z