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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexesStructures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complexRNA sequence and two-dimensional structure features required for efficient substrate modification by the Saccharomyces cerevisiae RNA:{Psi}-synthase Pus7p.Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase.Pseudouridylation of yeast U2 snRNA is catalyzed by either an RNA-guided or RNA-independent mechanism.The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs.P bodies: at the crossroads of post-transcriptional pathwaysQuality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decayAntagonistic factors control the unproductive splicing of SC35 terminal intron.MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decayCombined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAsMicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2.Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA.Enhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients.A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs.Use of specific chemical reagents for detection of modified nucleotides in RNA.P-body formation is a consequence, not the cause, of RNA-mediated gene silencing.A conserved splicing mechanism of the LMNA gene controls premature aging.Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 proteinFluorescence in situ hybridization of small non-coding RNAsProbing small non-coding RNAs structures
P50
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P50
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P106
P21
P31
P496
0000-0001-8909-0660