Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
about
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturationLoss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosisInteraction of phosphorylated c-Jun with TCF4 regulates intestinal cancer developmentNuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formationAP4 encodes a c-MYC-inducible repressor of p21Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stabilityThe role of peroxisome proliferator-activated receptors in carcinogenesis and chemopreventionEph/ephrin molecules--a hub for signaling and endocytosisWnt signaling, lgr5, and stem cells in the intestine and skinA genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expressionThe Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomasWnt signaling: the good and the badEmerging Molecular and Biological Functions of MBD2, a Reader of DNA MethylationFrizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerMouse models of intestinal cancerColorectal cancer models for novel drug discoveryReserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractG Protein-Coupled Receptor Signaling in Stem Cells and CancerTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28Animal models of colorectal cancerIntestinal tumor in a dishCrosstalk between Agrin and Wnt signaling pathways in development of vertebrate neuromuscular junctionComputational models reveal a passive mechanism for cell migration in the cryptDifferential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestineA comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal cryptStem cell competition in the gut: insights from multi-scale computational modellingInflammation and proliferation act together to mediate intestinal cell fusionUse of Cancer Stem Cells to Investigate the Pathogenesis of Colitis-associated CancerMouse models of colorectal cancer as preclinical modelsGenetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoA common role for various human truncated adenomatous polyposis coli isoforms in the control of beta-catenin activity and cell proliferationA critical role for Apc in hematopoietic stem and progenitor cell survivalDeficiency of Mbd2 attenuates Wnt signalingThe Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling programConserved mechanisms of tumorigenesis in the Drosophila adult midgutWnt5a is essential for intestinal elongation in miceTIGAR is required for efficient intestinal regeneration and tumorigenesisNotch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestineSox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
P2860
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P2860
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
description
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juni 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/06/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/06/15)
@nl
наукова стаття, опублікована в червні 2004
@uk
مقالة علمية (نشرت في 15-6-2004)
@ar
name
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@ast
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@en
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@nl
type
label
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@ast
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@en
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@nl
prefLabel
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@ast
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@en
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@nl
P2093
P2860
P3181
P356
P1433
P1476
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
@en
P2093
Alan R. Clarke
Anthony J. Hayes
Douglas J. Winton
Hannah Brinkmann
Hans Clevers
Heather Ireland
Ian P. Newton
Inke S. Nathke
Karen R. Reed
Patricia Simon-Assmann
P2860
P304
P3181
P356
10.1101/GAD.287404
P577
2004-06-15T00:00:00Z