Early onset photoreceptor abnormalities induced by targeted disruption of the interphotoreceptor retinoid-binding protein gene
about
Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP)An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanismsNeuroprotection as a Therapeutic Target for Diabetic RetinopathyCharacterization of a dehydrogenase activity responsible for oxidation of 11-cis-retinol in the retinal pigment epithelium of mice with a disrupted RDH5 gene. A model for the human hereditary disease fundus albipunctatus.Increased fibronectin deposition in embryonic hearts of retinol-binding protein-null miceLocalizations of visual cycle components in retinal pigment epitheliumInterphotoreceptor retinoid-binding protein gene structure in tetrapods and teleost fishA homozygous missense mutation in the IRBP gene (RBP3) associated with autosomal recessive retinitis pigmentosa.Exaggerated eye growth in IRBP-deficient mice in early developmentDisruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters.Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophiesThe retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy.Retinal degeneration in animal models with a defective visual cycle.Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site.The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein.Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding proteinInterphotoreceptor retinoid-binding protein protects retinoids from photodegradationThe living eye "disarms" uncommitted autoreactive T cells by converting them to Foxp3(+) regulatory cells following local antigen recognition.Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection.Spontaneous autoimmunity prevented by thymic expression of a single self-antigenEndogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunityRepertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) miceInterphotoreceptor Retinoid-Binding Protein Mitigates Cellular Oxidative Stress and Mitochondrial Dysfunction Induced by All-trans-Retinal.Retinol and retinyl esters: biochemistry and physiologyFold conservation and proteolysis in zebrafish IRBP structure: Clues to possible enzymatic function?Noncanonical autophagy promotes the visual cycleNew insights into retinoid metabolism and cycling within the retinaThe role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptorsIRBP deficiency permits precocious ocular development and myopia.Lighting a candle in the dark: advances in genetics and gene therapy of recessive retinal dystrophies.Normal cone function requires the interphotoreceptor retinoid binding protein.Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium.Interphotoreceptor retinoid-binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation.Impaired Rhodopsin Generation in the Rat Model of Diabetic Retinopathy.
P2860
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P2860
Early onset photoreceptor abnormalities induced by targeted disruption of the interphotoreceptor retinoid-binding protein gene
description
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Juni 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/06/15)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/06/15)
@nl
наукова стаття, опублікована в червні 1998
@uk
مقالة علمية (نشرت في 15-6-1998)
@ar
name
Early onset photoreceptor abno ...... retinoid-binding protein gene
@ast
Early onset photoreceptor abno ...... retinoid-binding protein gene
@en
Early onset photoreceptor abno ...... retinoid-binding protein gene
@nl
type
label
Early onset photoreceptor abno ...... retinoid-binding protein gene
@ast
Early onset photoreceptor abno ...... retinoid-binding protein gene
@en
Early onset photoreceptor abno ...... retinoid-binding protein gene
@nl
prefLabel
Early onset photoreceptor abno ...... retinoid-binding protein gene
@ast
Early onset photoreceptor abno ...... retinoid-binding protein gene
@en
Early onset photoreceptor abno ...... retinoid-binding protein gene
@nl
P2093
P3181
P1476
Early onset photoreceptor abno ...... retinoid-binding protein gene
@en
P2093
M E Gottesman
N S Peachey
S Matragoon
W S Blaner
P304
P3181
P356
10.1523/JNEUROSCI.18-12-04511.1998
P407
P577
1998-06-01T00:00:00Z