about
Patched1 interacts with cyclin B1 to regulate cell cycle progressionIndian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levelsThe structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingHomozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips.A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway.A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysisProteolytic processing yields two secreted forms of sonic hedgehogDifferential range and activity of various forms of the Hedgehog proteinTargeting the Hedgehog Pathway in Pediatric MedulloblastomaHedgehog Cholesterolysis: Specialized Gatekeeper to Oncogenic SignalingHedgehog signaling pathway in ovarian cancerHedgehog signaling and maintenance of homeostasis in the intestinal epitheliumMapping sonic hedgehog-receptor interactions by steric interferenceHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsHedgehog family member is expressed throughout regenerating and developing limbsBiography of Philip A. BeachyIdentification of conserved regions and residues within Hedgehog acyltransferase critical for palmitoylation of Sonic HedgehogSonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patchedMammalian Gup1, a homolog of Saccharomyces cerevisiae glycerol uptake/transporter 1, acts as a negative regulator for N-terminal palmitoylation of Sonic hedgehogDally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal responseA direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cordRenal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferaseWnt signaling interacts with Shh to regulate taste papilla developmentEmbryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targetingExpression of Sonic Hedgehog downstream genes is modified in rat embryos exposed in utero to a distal inhibitor of cholesterol biosynthesis.The NH2-terminal region of the active domain of sonic hedgehog is necessary for its signal transduction.Quantitative analysis of Hedgehog gradient formation using an inducible expression system.Evidence for a role of vertebrate Disp1 in long-range Shh signalingAnalysis of axonal trafficking via a novel live-imaging technique reveals distinct hedgehog transport kineticsA novel proteolytic event controls Hedgehog intracellular sorting and distribution to receptive fieldsActions of hedgehog proteins on skeletal cells.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Mechanism and evolution of cytosolic Hedgehog signal transductionLipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response.Identification and characterization of autosomal genes that interact with glass in the developing Drosophila eye.Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway.YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations.A new role for Hedgehogs in juxtacrine signaling.Differential involvement of Hedgehog signaling in butterfly wing and eyespot development.
P2860
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P2860
description
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1994
@ast
im Dezember 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/12/02)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/12/02)
@nl
наукова стаття, опублікована в грудні 1994
@uk
name
Autoproteolysis in hedgehog protein biogenesis
@ast
Autoproteolysis in hedgehog protein biogenesis
@en
Autoproteolysis in hedgehog protein biogenesis
@nl
type
label
Autoproteolysis in hedgehog protein biogenesis
@ast
Autoproteolysis in hedgehog protein biogenesis
@en
Autoproteolysis in hedgehog protein biogenesis
@nl
prefLabel
Autoproteolysis in hedgehog protein biogenesis
@ast
Autoproteolysis in hedgehog protein biogenesis
@en
Autoproteolysis in hedgehog protein biogenesis
@nl
P2093
P3181
P356
P1433
P1476
Autoproteolysis in hedgehog protein biogenesis
@en
P2093
D. P. von Kessler
J. A. Porter
P. A. Beachy
S. C. Ekker
P304
P3181
P356
10.1126/SCIENCE.7985023
P407
P577
1994-12-02T00:00:00Z