A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein
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Human La protein interaction with GCAC near the initiator AUG enhances hepatitis C Virus RNA replication by promoting linkage between 5' and 3' untranslated regionsInteraction cloning and characterization of RoBPI, a novel protein binding to human Ro ribonucleoproteins.A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulationA peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation.Structural Determinant of Human La Protein Critical for Internal Initiation of Translation of Hepatitis C Virus RNAStructure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patchStructural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La ProteinTwo yeast La motif-containing proteins are RNA-binding proteins that associate with polyribosomes.La protein and its associated small nuclear and nucleolar precursor RNAsReconstitution of transcription from the human U6 small nuclear RNA promoter with eight recombinant polypeptides and a partially purified RNA polymerase III complexRecognition of nascent RNA by the human La antigen: conserved and divergent features of structure and functionConserved and divergent features of the structure and function of La and La-related proteins (LARPs)5' processing of tRNA precursors can Be modulated by the human La antigen phosphoprotein.Efficient synthesis, termination and release of RNA polymerase III transcripts in Xenopus extracts depleted of La protein.Mammalian peptidylglycine alpha-amidating monooxygenase mRNA expression can be modulated by the La autoantigenKinetic trapping of DNA by transcription factor IIIBComparison of the RNA polymerase III transcription machinery in Schizosaccharomyces pombe, Saccharomyces cerevisiae and human.Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant.Human La is found at RNA polymerase III-transcribed genes in vivoTranscription termination by the eukaryotic RNA polymerase III.Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation3' processing of eukaryotic precursor tRNAs.La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast.Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms.Precursor-product discrimination by La protein during tRNA metabolism.Nonphosphorylated human La antigen interacts with nucleolin at nucleolar sites involved in rRNA biogenesis.Contributions of the individual domains in human La protein to its RNA 3'-end binding activity.Methylphosphate cap structure in small RNAs reduces the affinity of RNAs to La protein.Molecular characterization of the human La protein.hepatitis B virus RNA.B interaction in vitro.La protein has a positive effect on the translation of TOP mRNAs in vivo.Intracellular redistribution of truncated La protein produced by poliovirus 3Cpro-mediated cleavage.Transcription efficiency of human polymerase III genes in vitro does not depend on the RNP-forming autoantigen La.RNA chaperone activity of human La protein is mediated by variant RNA recognition motifHepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen.Human La binds mRNAs through contacts to the poly(A) tail.The La Motif and the RNA Recognition Motifs of Human La Autoantigen Contribute Individually to RNA Recognition and Subcellular Localization
P2860
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P2860
A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A carboxy-terminal basic regio ...... r activity of human La protein
@ast
A carboxy-terminal basic regio ...... r activity of human La protein
@en
type
label
A carboxy-terminal basic regio ...... r activity of human La protein
@ast
A carboxy-terminal basic regio ...... r activity of human La protein
@en
prefLabel
A carboxy-terminal basic regio ...... r activity of human La protein
@ast
A carboxy-terminal basic regio ...... r activity of human La protein
@en
P2093
P2860
P356
P1476
A carboxy-terminal basic regio ...... r activity of human La protein
@en
P2093
P2860
P304
P356
10.1128/MCB.17.10.5823
P407
P577
1997-10-01T00:00:00Z