Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome - Wikidata - awgldk - TriplyDB

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

http://www.wikidata.org/entity/Q29547419

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Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity TRPM2 links oxidative stress to NLRP3 inflammasome activation Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation The Mucosal Immune System and Its Regulation by Autophagy Interactions between Autophagy and Inhibitory Cytokines Resolution of Inflammation: What Controls Its Onset?A Cellular GWAS Approach to Define Human Variation in Cellular Pathways Important to Inflammation New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy Crosstalk between the heart and peripheral organs in heart failure Autophagy-associated immune responses and cancer immunotherapy Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway The Role of Stefin B in Neuro-inflammation MIF: Implications in the Pathoetiology of Systemic Lupus Erythematosus Looking for Pyroptosis-Modulating miRNAs as a Therapeutic Target for Improving Myocardium Survival Molecular mechanisms regulating NLRP3 inflammasome activation New mechanisms of metformin action: Focusing on mitochondria and the gut Reactive oxygen species and mitochondria: A nexus of cellular homeostasis Cellular and Molecular Connections between Autophagy and Inflammation NLRP3 Inflammasome and Pathobiology in AMD Microglial cell dysregulation in brain aging and neurodegeneration Interactions between Autophagy and Bacterial Toxins: Targets for Therapy?Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connection Autophagy and the regulation of the immune response Role of vascular smooth muscle cell in the inflammation of atherosclerosis NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?Reactive oxygen species at the crossroads of inflammasome and inflammation Redox regulation of mitochondrial biogenesis Regulation of mitochondrial biogenesis and its intersection with inflammatory responses The Potential Role of the NLRP3 Inflammasome as a Link between Mitochondrial Complex I Dysfunction and Inflammation in Bipolar Disorder NOD-Like Receptors: Master Regulators of Inflammation and Cancer Mitophagy: mechanisms, pathophysiological roles, and analysis

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P2860

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

http://www.wikidata.org/entity/Q29547419

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2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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Autophagy proteins regulate in ...... ated by the NALP3 inflammasome

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Nature Immunology

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Augustine M K Choi

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Hilaire C Lam

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Hong Pyo Kim

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Jeffrey Adam Haspel

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Katherine A Fitzgerald

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Kiichi Nakahira

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Manuela Cernadas

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Marlene Rabinovitch

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Seon-Jin Lee

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Stefan W Ryter

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P2860

Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure

IFI16 is an innate immune sensor for intracellular DNA

The inflammasomes

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Inflammasomes: too big to miss

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

Autophagy in the Pathogenesis of Disease

Mitochondrial calcium and the permeability transition in cell death

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands

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222-230

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601166

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10.1038/NI.1980

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3

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12

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Joshua A Englert

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2010-12-12T00:00:00Z

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49676816

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21151103

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mitochondrial DNA

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3079381

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