about
Origin and evolution of the peroxisomal proteome.Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.Peroxisome synthesis in the absence of preexisting peroxisomesIdentification and characterization of the human orthologue of yeast Pex14pHuman PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assemblyPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importPEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesisDefective peroxisome membrane synthesis due to mutations in human PEX3 causes Zellweger syndrome, complementation group GMultiple distinct targeting signals in integral peroxisomal membrane proteinsTwo proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrixThe dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11Requirement for microtubules and dynein motors in the earliest stages of peroxisome biogenesisPEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteinsThe membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assemblyStructural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3pThe peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathwayIdentification of a human PTS1 receptor docking protein directly required for peroxisomal protein importCloning and characterization of the gene encoding the human peroxisomal assembly protein Pex3pPEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteinsSec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cellsA role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells.Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disordersClofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen speciesThe origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ERGenetic evaluation of physiological functions of thiolase isoenzymes in the n-alkalane-assimilating yeast Candida tropicalisPEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12pTwo AAA family peroxins, PpPex1p and PpPex6p, interact with each other in an ATP-dependent manner and are associated with different subcellular membranous structures distinct from peroxisomes.Hsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.Pex19p, a farnesylated protein essential for peroxisome biogenesis.Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders.The peroxin pex3p initiates membrane assembly in peroxisome biogenesisHuman pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequencesGenetic heterogeneity in the cerebrohepatorenal (Zellweger) syndrome and other inherited disorders with a generalized impairment of peroxisomal functions. A study using complementation analysisGlycosome assembly in trypanosomes: variations in the acceptable degeneracy of a COOH-terminal microbody targeting signalHuman PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group IPeroxisome diversity and evolutionDisruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease
P2860
Q21203779-5E8B768A-0A60-4BD9-B3F1-220385AF67F1Q22008461-33D2AB0A-2529-4E4B-94CF-3E3D1D2485B6Q22008726-61E68065-F67D-42EE-A6D9-87B03DA08FE7Q22008763-A305014C-4ADB-4940-9BD4-17C950A67802Q22008838-8BDB6B6F-094A-4E2D-BBD7-7FB8EB9F3496Q22010795-E9A0A209-53BF-4C34-A253-DFA58ED1E6D2Q22253284-487CBA4E-46AF-4691-87BE-4943161E9FFEQ24290144-D6CA5575-D5EA-4149-A580-C1B58B46832AQ24291322-1AB280CA-7778-45B0-B162-535E80FAA1B8Q24293436-64AC8E3C-B160-4B62-A40B-F0AA03F9B577Q24296804-EF1A019E-E1D0-46B0-A6BB-40AFE9203613Q24299609-7504002F-26A0-47B2-8067-4F82848B70F2Q24304129-DE9987AE-885B-4AFB-8FAB-A48163F948FBQ24306509-AA4B848C-E440-46EE-845D-35F170511892Q24307906-7E5C74BB-A540-416F-B9BD-0820B129E760Q24311655-918E4E47-B9A5-41E7-9929-5B15BE7D9E99Q24312105-34BDE01B-AE9F-427F-816F-DDC6D0E27D00Q24313158-A8E4E24F-5031-4096-9F09-C03460F154ABQ24315009-423D78BF-7685-4E3D-B2B7-CC681B13E792Q24315632-031E5C30-D13C-4EE9-88C6-2B5B743620A9Q24315986-DE80DBE1-F51C-4958-B528-CAA9BE327EB7Q24318540-96CF1BF3-1FF8-4F7E-ABF1-972F78B40BD8Q24336400-1AC10F41-D620-459A-8754-C0E23F5F3716Q24336548-18D8BD49-FB20-45DA-ABB4-CEA6DC3FE7A4Q24337711-1EC27D88-1FA4-40D3-A832-226783B9E2DAQ24520583-F4CBBDC3-58E6-4D22-8396-99EC8D53615AQ24522572-AB3E37A5-4182-43E6-AB28-E8D2D96AF7FBQ24523953-55262A2A-172D-4DE1-9A5E-204DB2157C35Q24533332-7299304A-54B0-43E8-95D5-C3B489B727B2Q24533793-609D3EBD-ED4D-4110-8D4E-D964561095ACQ24533963-A17C0F10-7551-4B9A-9AC7-32B4906C1041Q24540037-D5F578D3-D40C-461A-80B4-D5F273F90439Q24540126-0388AAAE-F409-4787-811C-518A462A02FAQ24549973-D198A96D-D56D-44BF-B6ED-BEA417D9FDFFQ24550941-6C080F01-C8A1-4C19-90A7-38F5F50F0605Q24561552-C904CFEE-DFB3-40A4-9DAF-B7F958ABCD0DQ24642685-A9570278-7B7C-4443-96DA-050FD1BC7758Q24645143-1A40C9EF-BAC4-4204-8452-B4B8DB034E41Q24652946-DAE2C469-AC28-4B9F-B856-74B0C7C18F63Q24681184-159A6FDE-D5FD-4DAE-AE04-1C37EE07C898
P2860
description
1985 nî lūn-bûn
@nan
1985 թուականին հրատարակուած գիտական յօդուած
@hyw
1985 թվականին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Biogenesis of peroxisomes
@ast
Biogenesis of peroxisomes
@en
type
label
Biogenesis of peroxisomes
@ast
Biogenesis of peroxisomes
@en
prefLabel
Biogenesis of peroxisomes
@ast
Biogenesis of peroxisomes
@en
P3181
P1476
Biogenesis of peroxisomes
@en
P2093
P304
P3181
P356
10.1146/ANNUREV.CB.01.110185.002421
P407
P577
1985-01-01T00:00:00Z