Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor.
about
Packing contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor.Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor.Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering.An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's diseaseTransmembrane protein aptamers that inhibit CCR5 expression and HIV coreceptor functionThe E5 proteinsViral miniproteinsMapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor.Biologically active LIL proteins built with minimal chemical diversity.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein.Drugging Membrane Protein Interactions.A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor.Protein-protein interactions in the membrane: sequence, structural, and biological motifs.The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango.De novo selection of oncogenes.Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction.Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions.Screening for transmembrane association in divisome proteins using TOXGREEN, a high-throughput variant of the TOXCAT assayIn vitro dimerization of the bovine papillomavirus E5 protein transmembrane domain.The identification of a minimal dimerization motif QXXS that enables homo- and hetero-association of transmembrane helices in vivo.Regulation of C-C chemokine receptor 5 (CCR5) stability by Lys-197 and by transmembrane protein aptamers that target it for lysosomal degradation.
P2860
Q33289844-FA5613A6-A6BB-491B-8567-27F01121ECE8Q33482628-3F21F65E-B6C4-45C7-9C4D-E5209147E46DQ33530296-78E8CA98-C3C5-49BF-AE9B-54536CCDDFFBQ33768327-C6935BB9-F2D7-49D0-9031-E007D8C0DDD8Q33879010-B064080D-3C73-4BDA-81C1-43050A3F8640Q34343448-97521053-E5F9-414B-A453-65BE401CD410Q34754347-4570467C-4259-4D48-8F15-D4B0E902C80BQ35151120-6FAD4074-4D11-4A71-BEB2-2823E67B585AQ35161709-DA6C8862-D4F3-4667-94E6-457E3DDA7BB4Q35742172-72499E5C-123A-4910-9F9B-572F57590E3DQ35990329-7D90008D-915C-4CCD-B695-14CD86267A19Q36318177-D72ACECF-0725-4949-A09B-50EB09006C5DQ37143137-9FE31815-0CB3-4216-8F49-BDAF807D7026Q37189482-D28EC059-8DD7-457A-A19E-FB8FCEEC257CQ37210616-DD34ED16-A6CE-4FF1-8BFE-79EB1FF8115AQ37319770-B3E1482D-5E18-44DE-BEAD-EC1434295382Q37475038-6DBD9258-3256-4349-AB82-11CE4058F778Q39113585-1B78095B-E8B4-4246-A81D-9A9D6B720570Q40471258-D702704B-882C-4CFD-AEE7-19F0359B79DDQ41136759-0F149AB7-9974-475C-80F8-5023002149DFQ42633335-8F1E48E3-9C8D-4A89-BE5F-85211F606B2DQ43092375-71CB80E5-1E77-46D5-A8D4-6E8427BECF90Q46505751-320A5EAC-25A4-45B4-B561-2D9248214722Q52313852-D35829FE-EA42-439F-86D6-B3F5BE8F0A95
P2860
Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Selection and characterization ...... d growth factor beta receptor.
@ast
Selection and characterization ...... d growth factor beta receptor.
@en
type
label
Selection and characterization ...... d growth factor beta receptor.
@ast
Selection and characterization ...... d growth factor beta receptor.
@en
prefLabel
Selection and characterization ...... d growth factor beta receptor.
@ast
Selection and characterization ...... d growth factor beta receptor.
@en
P2093
P50
P1476
Selection and characterization ...... d growth factor beta receptor.
@en
P2093
Daniel DiMaio
Donald M Engelman
Jennifer B Frank
Lisa L Freeman-Cook
P304
P356
10.1016/J.JMB.2004.03.044
P407
P577
2004-05-01T00:00:00Z