Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.
about
Assembly of core helices and rapid tertiary folding of a small bacterial group I ribozymeAn obligate intermediate along the slow folding pathway of a group II intron ribozyme.Engineered external guide sequences are highly effective in inducing RNase P for inhibition of gene expression and replication of human cytomegalovirusA relaxed active site after exon ligation by the group I intronIn vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron.Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification.Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences.Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme.Refolding of rRNA exons enhances dissociation of the Tetrahymena intronIntracellular expression of engineered RNase P ribozymes effectively blocks gene expression and replication of human cytomegalovirusEngineered external guide sequences effectively block viral gene expression and replication in cultured cells.Total chemical synthesis of a ribozyme derived from a group I intron.Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.Engineered external guide sequences are highly effective in inhibiting gene expression and replication of hepatitis B virus in cultured cells.Effective inhibition of Rta expression and lytic replication of Kaposi's sarcoma-associated herpesvirus by human RNase P.Kinetic analysis of the 5' splice junction hydrolysis of a group II intron promoted by domain 5.Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.Fingerprinting the folding of a group I precursor RNAThermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozymeCooperative and anticooperative binding to a ribozyme.Use of intrinsic binding energy for catalysis by an RNA enzymeRNase P-associated external guide sequence effectively reduces the expression of human CC-chemokine receptor 5 and inhibits the infection of human immunodeficiency virus 1Rational screening of oligonucleotide combinatorial libraries for drug discovery.RNA structure and NMR spectroscopy.Inhibition of hepatitis B virus gene expression and replication by ribonuclease P.A trinucleotide can promote metal ion-dependent specific cleavage of RNA.Magnesium-dependent folding of self-splicing RNA: exploring the link between cooperativity, thermodynamics, and kineticsRescue of abasic hammerhead ribozymes by exogenous addition of specific basesEvidence for U-tail stabilization of gRNA/mRNA interactions in kinetoplastid RNA editing.Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.In vitro selection of external guide sequences for directing RNase P-mediated inhibition of viral gene expression.RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture.Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments.Molecular recognition properties of IGS-mediated reactions catalyzed by a Pneumocystis carinii group I intron.Ribonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences.An RNA fragment consisting of the P7 and P9.0 stems and the 3'-terminal guanosine of the Tetrahymena group I intron.Bulged-out nucleotides in an antisense RNA are required for rapid target RNA binding in vitro and inhibition in vivoGel retardation analysis of E. coli M1 RNA-tRNA complexes.
P2860
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P2860
Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@ast
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@en
type
label
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@ast
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@en
prefLabel
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@ast
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@en
P2093
P2860
P356
P1476
Direct measurement of oligonuc ...... nt ribozymes from Tetrahymena.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.21.8187
P407
P577
1990-11-01T00:00:00Z