Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission. - Wikidata - awgldk - TriplyDB

Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.

Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.

http://www.wikidata.org/entity/Q30544664

about

Cytokinetic abscission is an acute G1 event.Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF.Controlling the switches: Rho GTPase regulation during animal cell mitosis.Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1.Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.Myosin II-interacting guanine nucleotide exchange factor (MYOGEF) promotes bleb retraction via stimulating cortex reassembly at the bleb membrane.

P2860

Q30669902-11280884-6E90-44AD-A5DE-A0E12120ADB5 Q34160731-0BAB31F6-A46F-4AFD-810D-3D28FAC1727A Q34634197-42606E4F-A674-432D-B157-1B3A80EE69E2 Q35580822-57AD13E9-439F-43FA-B85D-45054D106339 Q37622664-06B0CC82-A5DB-4DD3-8B2B-C59CB652C24B Q38257062-5EFD4CA2-62EF-4B8B-B240-B7B5A0F5AE31 Q40413517-F05D606E-00FB-4B19-BC70-5442F4933ABF Q42635576-047FBCD6-40C1-4F71-9EE5-7FEF0233C622 Q48517897-4EBF892B-41AA-46D0-8FFB-8FFFA89C4811

P2860

Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.

http://www.wikidata.org/entity/Q30544664

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@ast

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@en

type

label

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@ast

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@en

prefLabel

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@ast

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@en

P1433

Q30544664-A834BA98-6C05-4D1A-A510-4DDE1DDD27CD

P1476

Q30544664-E958C734-D1D4-4980-9DA6-7C4C91C6C98A

P2093

Q30544664-660CD525-4BFF-4BFB-A546-F48E40EBE776

Q30544664-84CFB429-7C4F-4A03-89B4-7D9588861141

Q30544664-8E870105-C491-4459-B0C9-3D401D29A64B

Q30544664-AB2D6F96-0641-4862-8CB2-27ED8FBF6403

P2860

Q30544664-042ACCBE-0737-40C9-8FFA-E9FFF37E892B

Q30544664-16BDDE12-5A68-42A5-B224-7B1D906F7216

Q30544664-218B5904-5362-4361-8174-A7F3617EF719

Q30544664-259503E2-1DCC-445F-84C7-88902CDF6361

Q30544664-30D0D242-7581-4340-B458-8EB2C78B3557

Q30544664-37254704-DF4B-4285-82FE-613FF943BCAF

Q30544664-3E5A0499-BB28-4B07-B502-6DA8CF9C1C07

Q30544664-41B14E4E-B2BF-410E-AB29-415161BDD17F

Q30544664-4297B57C-2486-46A8-B2F5-C140CAEF3A59

Q30544664-46DB3F1C-3338-43EA-AE81-29A9D80B8E6A

P304

Q30544664-0B8B4BA4-CC45-4D10-8052-D8C41B1128DD

P31

Q30544664-0FBA96A7-C024-4271-AE76-FAEC84BF1B54

P356

Q30544664-C2A1FA84-1D9B-45C5-8FE3-A28D82E18A7F

P433

Q30544664-252A7473-0CF9-4050-A760-0C09DB534E2A

P478

Q30544664-6C125207-F8EB-4E40-92F8-605B543F1157

P50

Q30544664-8EC66A17-1B05-49EE-99D3-9F113607DA13

P577

Q30544664-DFD79D7E-E709-426C-9B9A-454F628EEF16

P698

Q30544664-364A98D7-EACE-427B-B4A8-8C10E4711F0B

P932

Q30544664-14642E4F-8C39-4B54-A254-60B7CAF5C4AF

P356

MBC.E12-07-0533

P1433

Molecular Biology of the Cell

P1476

Leukemia-associated RhoGEF (LA ...... oper completion of abscission.

@en

P2093

Elda Grabocka

http://www.w3.org/2001/XMLSchema#string

Matthew K Martz

http://www.w3.org/2001/XMLSchema#string

Neil Beeharry

http://www.w3.org/2001/XMLSchema#string

Philip B Wedegaertner

http://www.w3.org/2001/XMLSchema#string

P2860

Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation

Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

Centrosome/spindle pole-associated protein regulates cytokinesis via promoting the recruitment of MyoGEF to the central spindle.

An ECT2-centralspindlin complex regulates the localization and function of RhoA

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

P304

2785-2794

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1091/MBC.E12-07-0533

http://www.w3.org/2001/XMLSchema#string

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-07-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23885121

http://www.w3.org/2001/XMLSchema#string

P932

3771942

http://www.w3.org/2001/XMLSchema#string